机构

• 上海药物研究所 [242]

采集方式

• OAI收割 [242]

内容类型

• 期刊论文 [237]
• 会议论文 [4]
• 专著章节 [1]

发表日期

• 2024 [5]
• 2023 [18]
• 2022 [10]
• 2021 [21]
• 2020 [16]
• 2019 [22]
• 更多

学科主题

• Pharmacolo... [3]
• Biochemist... [2]
• Chemistry [1]
• Neuroscien... [1]
• Plant Scie... [1]

筛选

浏览/检索结果: 共242条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser56 to diminish pancreatic β cell function upon overnutrition 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16 作者:  Lu, Yuting;  Xu, Junyu;  Li, Yufeng;  Wang, Ruoran;  Dai, Chengqiu   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/13 Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14 作者:  Tao, Yimin;  Lu, Wei;  Gao, Jinli;  Yang, Shuangshuang;  Ruan, Chaoyi   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/13 antibody-drug conjugate (ADC)  bioanalysis  anti-drug antibody (ADA)  ligand binding assay (LBA)  ADA-tolerant assay   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Low-Dose Chemotherapy Preferentially Shapes the Ileal Microbiome and Augments the Response to Immune Checkpoint Blockade by Activating AIM2 Inflammasome in Ileal Epithelial Cells 期刊论文  OAI收割 ADVANCED SCIENCE, 2024, 页码: 17 作者:  Pu, Congying;  Li, Yize;  Fu, Yixian;  Yan, Yiyang;  Tao, Siyao   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/02/27 AIM2 inflammasome  chemotherapy  gut microbiome  ileal epithelial cells  immune checkpoint blockade  lactobacillus  segmented filamentous bacterium   Structure-Guided Design, Synthesis, and Antivirulence Assessment of Covalent Staphylococcus aureus Sortase A Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1127-1146 作者:     |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/27 Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Deng, Minjie;  Gao, Yue;  Wang, Peipei;  Du, Wenjing;  Xu, Gaoya   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/19 An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21 作者:  Wang, Jingyi;  Lin, Jianbang;  Chen, Yefei;  Liu, Jing;  Zheng, Qiongping   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/01/16 Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12 作者:  Tang, Shuai   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 KRAS  Pancreatic ductal adenocarcinoma  MAPK pathway  Tetrandrine  TRAIL  Death receptors   Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma 期刊论文  OAI收割 Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556 作者:  Yuan, Hong-Kai;  Li, Bo;  Wu, Leyun;  Wang, Xue-Ling;  Lv, Zhi-Ying   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/03/26 Active learning  Consensus labelling  Eye irritation  Serious eye damage  Structural alerts   Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 14 作者:  Li, Cuixia;  Wu, Yiran;  Wang, Wenli;  Xu, Lu;  Zhou, Yan   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17