中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2023 [3]
2022 [4]
2018 [2]
2014 [2]
2012 [2]
学科主题
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共13条,第1-10条
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专题:上海药物研究所
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Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:
Zhang, Yong-mei
;
Zong, Hai-chao
;
Qi, Ying-bei
;
Chang, Liu-liu
;
Gao, Ya-nan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
GPCR activation and GRK2 assembly by a biased intracellular agonist
期刊论文
OAI收割
NATURE, 2023, 页码: 27
作者:
Duan, Jia
;
Liu, Heng
;
Zhao, Fenghui
;
Yuan, Qingning
;
Ji, Yujie
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
The Effects of a Transgelin-2 Agonist Administered at Different Times in a Mouse Model of Airway Hyperresponsiveness
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 8
作者:
Yuan, Hong-Kai
;
Lu, Jin
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
;
Li, Bo
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/16
transgelin-2
agonist
TSG12
administration time
asthma
airway hyperresponsiveness
Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 12
作者:
Xu, Youwei
;
Wu, Canrong
;
Cao, Xiaodan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
Quinotine alkaloids with anti-inflammatory activity from Zanthoxylum avicennae
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 页码: 7
作者:
Ji, Kai-Long
;
Liu, Wei
;
Yin, Wei-Hang
;
Li, Jing-Ya
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody
期刊论文
OAI收割
SCIENCE, 2022, 卷号: 375, 期号: 6584, 页码: 1048-+
作者:
Yin, Wanchao
;
Xu, Youwei
;
Xu, Peiyu
;
Cao, Xiaodan
;
Wu, Canrong
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
Discovery of FS36 as a Novel Human Hsp90 Inhibitor
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2018, 卷号: 45, 期号: 7, 页码: 736-744
作者:
Li Gen
;
Lu Kai-Kai
;
Li Jian
;
Yin Xiu-Shan
;
Zhao Dong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
heat shock protein 90
antitumor drugs
inhibitor
X-ray diffraction
complex crystal structure
The HNF1 alpha-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1
期刊论文
OAI收割
MOLECULAR CANCER, 2018, 卷号: 17
作者:
Ding, Chen-Hong
;
Yin, Chuan
;
Chen, Shi-Jie
;
Wen, Liang-Zhi
;
Ding, Kai
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
HNF1 alpha
HNF1A-AS1
Hepatocellular carcinoma
SHP-1
phosphatase activity
Novel Bayesian classification models for predicting compounds blocking hERG potassium channels
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 8, 页码: 1093-1102
作者:
Liu, Li-li
;
Lu, Jing
;
Lu, Yin
;
Zheng, Ming-yue
;
Luo, Xiao-min
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
hERG
potassium channels
long QT syndrome
pharmacophore
modeling
Laplacian-modified Bayesian
extended-connectivity fingerprints
QSAR