中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [106]
采集方式
OAI收割 [106]
内容类型
期刊论文 [105]
会议论文 [1]
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2024 [2]
2023 [6]
2022 [9]
2021 [10]
2020 [8]
2019 [6]
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浏览/检索结果:
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专题:上海药物研究所
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Intelligent design and construction of novel APN-based theranostic probe driven by advanced computational methods
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 2, 页码: 6
作者:
Zhu, Yingli
;
Qian, Jie
;
Yu, Kunqian
;
Hou, Jing
;
Ma, Yeshuo
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/26
Theranostic probe
Artificial intelligence
Conformational restriction
Fluorescence restoration
Design strategy
Pharmacologically significant constituents collectively responsible for anti-sepsis action of XueBiJing, a Chinese herb-based intravenous formulation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 16
作者:
Cheng, Chen
;
Ren, Chao
;
Li, Mu-zi
;
Liu, Yi-hui
;
Yao, Ren-qi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Traditional Chinese medicine
XueBiJing
sepsis
mortality
pharmacokinetic compatibility
polypharmacology
Alpha-Emitter Radium-223 Induces STING-Dependent Pyroptosis to Trigger Robust Antitumor Immunity
期刊论文
OAI收割
SMALL, 2023, 页码: 15
作者:
Yang, Mengdie
;
Liu, Haipeng
;
Lou, Jingjing
;
Zhang, Jiajia
;
Zuo, Changjing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
alpha-emitter
immunogenic cell death
pyroptosis
radium-223
stimulator of interferon genes (STING)
The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 12
作者:
Zhou, Jiashen
;
Zhang, Lin
;
Wang, Yiran
;
Song, Wenyan
;
Huang, Yuzhou
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/08
Acyl-ACP Reductases
Allosteric Regulation
Biosynthesis
Enantioselective Reduction
Enzyme Catalysis
Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16
作者:
Yang, Ze-xian
;
Zhang, Yu
;
Wang, Qing
;
Zhang, Lei
;
Liu, Yi-fei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Parkinson's disease
gut-brain axis
a-Synuclein
inflammation
microbiota
intestinal mouse coloclysis model
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925
作者:
Zhou, Wei
;
Fang, Peng
;
Yu, Dongan
;
Ren, Hongyuan
;
You, Meng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Full title: Rational Design of Organelle-targeted Fluorescent Probes: Insights from Artificial Intelligence
期刊论文
OAI收割
RESEARCH, 2023, 卷号: 2023, 页码: 33
作者:
Dong, Jie
;
Qian, Jie
;
Yu, Kunqian
;
Huang, Shuai
;
Cheng, Xiang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Redox-neutral rhodium(iii)-catalyzed divergent synthesis of tetrasubstituted 1,3-enynes and alkynylated benzofurans
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 1, 页码: 147-152
作者:
Gong, Xin
;
Yu, Na
;
Gu, Linghui
;
Li, Zheyu
;
Ma, Wenbo
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Deffini: A family-specific deep neural network model for structure-based virtual screening
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 151, 页码: 8
作者:
Zhou, Dixin
;
Liu, Fei
;
Zheng, Yiwen
;
Hu, Liangjian
;
Huang, Tao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/04/10
Virtual screening
Protein family -specific model
Structure -based
Convolutional neural network
Drug discovery
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 19
作者:
Hu, Cheng-Long
;
Chen, Bing-Yi
;
Li, Zijuan
;
Yang, Tianbiao
;
Xu, Chun-Hui
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13