中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [75]
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OAI收割 [75]
内容类型
期刊论文 [74]
会议论文 [1]
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2024 [3]
2023 [2]
2022 [5]
2021 [8]
2020 [3]
2019 [5]
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专题:上海药物研究所
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An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG
期刊论文
OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:
Liu, Zhipei
;
Wang, Feng
;
Yuan, Hui
;
Tian, Fuyun
;
Yang, Chuanyan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/13
hERG
K525N
Gating Polarity
Voltage-Sensing Domain
LQT2
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 170, 页码: 6
作者:
Fan, Shu-Hui
;
Chang, Yuan
;
Xiong, Xiao-Yu
;
Xiang, Mai
;
Yuan, Wen-Long
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/27
DZ2002
Osteoarthritis
Osteoclast
Bone resorption
Clinically Translatable Solid-State Dye for NIR-II Imaging of Medical Devices
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 13
作者:
Li, Deling
;
Shi, Hui
;
Qi, Qingrong
;
Chang, Baisong
;
Jiang, Yuanwen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/19
aggregates
in vivo imaging
medical devices
NIR-II fluorescence
YCH1899, a Highly Effective Phthalazin-1(2H)-one Derivative That Overcomes Resistance to Prior PARP Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 20
作者:
Sun, Yuting
;
Yang, Hui
;
Yuan, Jiaqi
;
Wang, Limin
;
Song, Shanshan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Research progress on effects of traditional Chinese medicine on myocardial ischemia-reperfusion injury: A review
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 23
作者:
Xing, Na
;
Long, Xiao-Tong
;
Zhang, Hui-Juan
;
Fu, Li-Dan
;
Huang, Jian-Yuan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
myocardial ischemia-reperfusion injury
pathogenesis
traditional Chinese medicine
cardioprotective effects
molecular mechanisms
Nanosized drug delivery systems modulate the immunosuppressive microenvironment to improve cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Yan, Wen-lu
;
Lang, Tian-qun
;
Yuan, Wen-hui
;
Yin, Qi
;
Li, Ya-ping
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/09/30
immunotherapy
nanosized drug delivery systems (NDDSs)
immunosuppressive tumor microenvironment (ITME)
immunogenetic cell death (ICD)
tumor vaccine
Development and validation of an LC-MS/MS method for simultaneous determination of remdesivir and its hydrolyzed metabolite and nucleoside, and its application in a pharmacokinetic study of normal and diabetic nephropathy mice
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2022, 页码: 10
作者:
Yuan, Meng
;
Hu, Wenjuan
;
Feng, Yingying
;
Tong, Yue
;
Wang, Xin
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
diabetic nephropathy
LC-MS
MS
nucleoside
pharmacokinetics
remdesivir
Selective bromodomain and extra-terminal bromodomain inhibitor inactivates macrophages and hepatic stellate cells to inhibit liver inflammation and fibrosis
期刊论文
OAI收割
BIOENGINEERED, 2022, 卷号: 13, 期号: 4, 页码: 10914-10930
作者:
Fu, Rong
;
Zu, Shi-Jia
;
Liu, Yan-Jun
;
Li, Jia-Cheng
;
Dang, Wen-Zhen
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/06/15
BET inhibitor
macrophage
hepatic stellate cell
inflammation
fibrosis
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy subjects
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 9
作者:
Qian, Hong-jie
;
Wang, Yu
;
Zhang, Meng-qi
;
Xie, Yuan-chao
;
Wu, Qing-qing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
VV116
nucleoside analog
SARS-CoV-2
safety
pharmacokinetics
healthy subjects