中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [16]
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Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma 期刊论文  OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:  
Yuan, Hong-Kai;  Li, Bo;  Wu, Leyun;  Wang, Xue-Ling;  Lv, Zhi-Ying
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/03/26
The Effects of a Transgelin-2 Agonist Administered at Different Times in a Mouse Model of Airway Hyperresponsiveness 期刊论文  OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 8
作者:  
Yuan, Hong-Kai;  Lu, Jin;  Wang, Xue-Ling;  Lv, Zhi-Ying;  Li, Bo
  |  收藏  |  浏览/下载:53/0  |  提交时间:2022/08/16
Targeted delivery of maytansine to liver cancer cells via galactose-modified supramolecular two-dimensional glycomaterial 期刊论文  OAI收割
CHEMICAL COMMUNICATIONS, 2022, 卷号: 58, 期号: 32, 页码: 5029-5032
作者:  
  |  收藏  |  浏览/下载:20/0  |  提交时间:2022/06/15
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  
Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan
  |  收藏  |  浏览/下载:92/0  |  提交时间:2020/12/24
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:  
Fan, Lei;  Qiu, Xiao-xia;  Zhu, Zhi-yuan;  Lv, Jian-lu;  Lu, Jian
  |  收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
Facilitating Anti-Cancer Combinatorial Drug Discovery by Targeting Epistatic Disease Genes 期刊论文  OAI收割
Molecules (Basel, Switzerland), 2018, 卷号: 23, 期号: 4
作者:  
Quan, Yuan;  Liu, Meng-Yuan;  Liu, Ye-Mao;  Zhu, Li-Da;  Wu, Yu-Shan
  |  收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119
作者:  
Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Wang, Yi-yang;  Xu, Xin
  |  收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 9-28
作者:  
Li, Cong;  Gu, Xiao-dan;  Lei, Min;  Wu, Jia-yi;  Jin, Jia-zhen
  |  收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:  
Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Xu, Xin;  Zhu, Zhi-yuan
  |  收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha) in Stabilizing the Homodimerization of the Receptor 期刊论文  OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 32, 页码: 19888-19899
作者:  
Xu, Xing;  Xu, Xin;  Liu, Peng;  Zhu, Zhi-yuan;  Chen, Jing
  |  收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08