中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [16]
采集方式
OAI收割 [16]
内容类型
期刊论文 [15]
会议论文 [1]
发表日期
2023 [1]
2022 [2]
2020 [1]
2019 [1]
2018 [1]
2017 [2]
更多
学科主题
筛选
浏览/检索结果:
共16条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
发表日期升序
发表日期降序
题名升序
题名降序
作者升序
作者降序
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
The Effects of a Transgelin-2 Agonist Administered at Different Times in a Mouse Model of Airway Hyperresponsiveness
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 8
作者:
Yuan, Hong-Kai
;
Lu, Jin
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
;
Li, Bo
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/16
transgelin-2
agonist
TSG12
administration time
asthma
airway hyperresponsiveness
Targeted delivery of maytansine to liver cancer cells via galactose-modified supramolecular two-dimensional glycomaterial
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2022, 卷号: 58, 期号: 32, 页码: 5029-5032
作者:
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/15
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
  |  
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice
Facilitating Anti-Cancer Combinatorial Drug Discovery by Targeting Epistatic Disease Genes
期刊论文
OAI收割
Molecules (Basel, Switzerland), 2018, 卷号: 23, 期号: 4
作者:
Quan, Yuan
;
Liu, Meng-Yuan
;
Liu, Ye-Mao
;
Zhu, Li-Da
;
Wu, Yu-Shan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Wang, Yi-yang
;
Xu, Xin
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
LX2343
cognitive deficits
oxidative stress
tauopathy
mitochondria
GSK-3 beta inhibitor
neuroprotection
ICV-STZ rats
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both A beta and Tau pathologies
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 1, 页码: 9-28
作者:
Li, Cong
;
Gu, Xiao-dan
;
Lei, Min
;
Wu, Jia-yi
;
Jin, Jia-zhen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Alzheimer's disease
Thamnolia vermicularis
SH-SY5Y cells
APP/PS1 transgenic mice
senile plaque
cognition
amyloid-beta
Tau
autophagy
BACE1
GSK3 beta
PI3K
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Xu, Xin
;
Zhu, Zhi-yuan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Alzheimer's disease
N-(1,3-benzodioxol-5-yl)-2-[5-chloro-2-methoxy(phenylsulfonyl)anilino]acetamide (LX2343)
streptozotocin
amyloid beta
BACE1
PI3K
autophagy
APP/PS1 transgenic mice
cognitive deficit
Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha) in Stabilizing the Homodimerization of the Receptor
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 32, 页码: 19888-19899
作者:
Xu, Xing
;
Xu, Xin
;
Liu, Peng
;
Zhu, Zhi-yuan
;
Chen, Jing
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08