机构

• 上海药物研究所 [55]

采集方式

• OAI收割 [55]

内容类型

• 期刊论文 [55]

发表日期

• 2024 [1]
• 2023 [8]
• 2022 [4]
• 2021 [5]
• 2020 [1]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共55条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15 作者:  Yan, Xue;  Zhang, Chun;  Gao, Li-Xin;  Liu, Min -Min;  Yang, Yu-Ting   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 Imidazo[124] triazole derivatives  Fluorescence property  SHP1  Bioactivity  Cellular imaging   Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12 作者:  Lin, Ting-ting;  Xiong, Wei;  Chen, Gui-hua;  He, Yang;  Long, Li   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26 osimertinib resistance  targeted drug delivery  liposomes  panobinostat  tumor-associated macrophage  combination therapy   Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   Deubiquitylating Enzymes in Cancer and Immunity 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 页码: 37 作者:  Ren, Jiang;  Yu, Peng;  Liu, Sijia;  Li, Ran;  Niu, Xin   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 cancer  deubiquitylating enzymes (DUBs)  immunity  therapeutic approach   Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925 作者:  Zhou, Wei;  Fang, Peng;  Yu, Dongan;  Ren, Hongyuan;  You, Meng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Design, Synthesis and Evaluation of Fluorescent Properties of Benzothiazole Derivatives 期刊论文  OAI收割 CHEMPHYSCHEM, 2023, 页码: 13 作者:  Sun, Yi-Tao;  Zhang, Chun;  Gao, Li-Xin;  Liu, Min-Min;  Yang, Yuting   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4 作者:  Cao, Bi-rong;  Huang, Yi-ming;  Tian, Fu-yun;  Li, Jin-hui;  Xu, Chun-long   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 Discovery of orally effective and safe GPR40 agonists by incorporating a chiral, rigid and polar sulfoxide into 8-position to the carboxylic acid 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115267 作者:  Chen, Cheng;  Guo, Shi-Meng;  Sun, Yuanjun;  Li, He;  Hu, Nan   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/03/27 GPR40  Glucose-stimulated insulin secretion  Type 2 diabetes mellitus  Lipophilicity  Liver safety  Three-in-one pharmacophore  2-(phenylsulfinyl)acetic acid   Extracellular vesicles mediate antibody-resistant transmission of SARS-CoV-2 期刊论文  OAI收割 CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15 作者:  Xia, Bingqing;  Pan, Xiaoyan;  Luo, Rong-Hua;  Shen, Xurui;  Li, Shuangqu   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10 Molecular Basis Underlying Hepatobiliary and Renal Excretion of Phenolic Acids of Salvia miltiorrhiza Roots (Danshen) 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 13 作者:  Lu, Jun-Lan;  Zeng, Xue-Shan;  Zhou, Xin;  Yang, Jun-Ling;  Ren, Ling-Ling   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 Danshen  Salvia miltiorrhiza  phenolic acid  hepatic transporter  renal transporter