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浏览/检索结果: 共14条，第1-10条 帮助

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From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:  Chen, Yi;  Liu, Qiu-pei;  Xie, Hua;  Ding, Jian
  |  收藏  |  浏览/下载：27/0  |  提交时间：2024/01/16
Drug design targeting active posttranslational modification protein isoforms 期刊论文  OAI收割
MEDICINAL RESEARCH REVIEWS, 2021, 卷号: 41, 期号: 3, 页码: 1701-1750
作者:  Meng, Fanwang;  Liang, Zhongjie;  Zhao, Kehao;  Luo, Cheng
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/22
Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020) 期刊论文  OAI收割
CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842
作者:  Wu, Jingwei;  Zhang, Huan;  Zhao, Guilong;  Wang, Runling
  |  收藏  |  浏览/下载：15/0  |  提交时间：2021/08/17
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
  |  收藏  |  浏览/下载：11/0  |  提交时间：2020/07/01
3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/ STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文  OAI收割
中国药理学报:英文版, 2019, 卷号: 40.0, 期号: 012, 页码: 1578
作者:  Hui Shan;  Sheng Yao;  Yang Ye;  Qiang Yu
  |  收藏  |  浏览/下载：9/0  |  提交时间：2020/12/24
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling 期刊论文  OAI收割
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:  Chen, Jianzhong;  Peng, Cheng;  Wang, Jinan;  Zhu, Weiliang
  |  收藏  |  浏览/下载：59/0  |  提交时间：2019/01/08
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 125, 页码: 1051-1063
作者:  Zhang, Feng-Hua;  Debnath, Bikash;  Xu, Zhong-Liang;  Yang, Liu-Meng;  Song, Li-Rui
  |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08
Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction 期刊论文  OAI收割
European Journal of Medicinal Chemistry, 2017, 卷号: 125, 期号: X, 页码: 1051-1063
作者:  Zhang FH;  Debnath B;  Zheng YT;  Neamati N[*];  Long YQ[*]
收藏  |  浏览/下载：72/0  |  提交时间：2016/11/07
Crystal structures of sirt3 reveal that the alpha 2-alpha 3 loop and alpha 3-helix affect the interaction with long-chain acyl lysine 期刊论文  iSwitch采集
Febs letters, 2016, 卷号: 590, 期号: 17, 页码: 3019-3028
作者:  Gai, Wei;  Li, He;  Jiang, Hualiang;  Long, Yaqiu
收藏  |  浏览/下载：38/0  |  提交时间：2019/05/09
DNA methyltransferase inhibitors: an updated patent review (2012-2015) 期刊论文  OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2016, 卷号: 26, 期号: 9, 页码: 1017-1030
作者:  Xu, Pan;  Hu, Guang;  Luo, Cheng;  Liang, Zhongjie
  |  收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08