中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [66]
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浏览/检索结果:
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SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Synthesis, and biological evaluation of EGFR/HER2-NAMPT conjugates for tumor treatment
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2023, 页码: 20
作者:
Ding, Mengyuan
;
Shen, Qianqian
;
Lu, Wei
;
Zhu, Shulei
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2023/10/17
EGFR
HER2
NAMPT
Resistance
Selectivity
Molecular docking
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 卷号: 61
作者:
Guo, Huihui
;
Zhang, Xilin
;
Xie, Shangzhi
;
Chen, Tianwei
;
Xie, Dong
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2022/12/22
gefitinib
CD28H
NSCLC
EGFR mutation
The effect of EGFR-TKIs on survival in advanced non-small-cell lung cancer with EGFR mutations: A real-world study
期刊论文
OAI收割
CANCER MEDICINE, 2022
作者:
Yu, Xiaoqing
;
Si, Jinfei
;
Wei, Jingwen
;
Wang, Yanling
;
Sun, Yan
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2022/12/23
EGFR-TKIs
non-small cell lung cancer (NSCLC)
real-world study
survival outcome
A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling
期刊论文
OAI收割
GLYCOCONJUGATE JOURNAL, 2022, 页码: 11
作者:
Liao, Wenfeng
;
Hu, Xiaodong
;
Du, Zhenyun
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2022/12/13
Homogalacturonan
Angiogenesis
Lonicera japonica
EGFR/Raf/MEK/ERK signaling cascade
Dll4/Notch1 signaling
Design, synthesis and evaluation of the Brigatinib analogues as potent inhibitors against tertiary EGFR mutants (EGFR(del19/T790M/C797S) and EGFR(L858R/T790M/C797S))
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 72, 页码: 11
作者:
Fang, Haotian
;
Wu, Yingming
;
Xiao, Qitao
;
He, Dongbo
;
Zhou, Tongrui
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/08/16
Non-small cell lung cancer
EGFR
Triple mutations
C797S
EGFR-TKIs
A Phase 2 Study of Befotertinib in Patients with EGFR T790M Mutated NSCLC after Prior EGFR TKIs
期刊论文
OAI收割
JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17
作者:
Lu, S.
;
Zhang, Y.
;
Zhang, G.
;
Zhou, J.
;
Cang, S.
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/12/23
third-generation EGFR-TKI
befotertinib
T790M
High-dose Aumolertinib as First-line Treatment in Patients With Brain Metastases Associated With EGFR Mutated NSCLC
期刊论文
OAI收割
JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17
作者:
Fan, Y.
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2022/12/23
NSCLC
EGFR TKI
Brain Metastases
Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib
期刊论文
OAI收割
BMC CANCER, 2022, 卷号: 22
作者:
Jin, Ying
;
Lin, Chen
;
Shi, Xun
;
He, Qiong
;
Yan, Junrong
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2022/12/23
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib