机构

• 上海药物研究所 [25]

采集方式

• OAI收割 [25]

内容类型

• 期刊论文 [25]

发表日期

• 2023 [25]

学科主题

筛选

浏览/检索结果: 共25条，第1-10条 帮助 限定条件 发表日期：2023    内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 From bench to bedside: current development and emerging trend of KRAS-targeted therapy 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18 作者:  Chen, Yi;  Liu, Qiu-pei;  Xie, Hua;  Ding, Jian   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/01/16 KRAS mutation  KRAS(G12C) inhibitor  Pan-KRAS inhibitor  SHP2 allosteric inhibitor  SOS1 inhibitor  combination therapy   Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764 作者:  Liu, Yingqiang;  Zhan, Zhengsheng;  Kang, Zhuang;  Li, Mengyuan;  Lv, Yongcong   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/01/26 Small molecule inhibitor  Tumor microenvironment  Immune-checkpoint  immune-deficient mouse models  including temozolomide (TMZ) insensitive tumors. Notably   High-throughput design of energetic molecules 期刊论文  OAI收割 JOURNAL OF MATERIALS CHEMISTRY A, 2023, 卷号: 11, 期号: 45, 页码: 25031-25044 作者:  Liu, Jian;  Zhao, Shicao   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/19 Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18 作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 Cancer immunotherapy  HPK1  Structure -based design  HPK1 inhibitor   Molecular basis of ClC-6 function and its impairment in human disease 期刊论文  OAI收割 SCIENCE ADVANCES, 2023, 卷号: 9, 期号: 41, 页码: 15 作者:     |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane 期刊论文  OAI收割 PHYTOMEDICINE, 2023, 卷号: 119, 页码: 14 作者:     |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 Liang-Ge-San  Dengue virus serotype 2  Heat shock protein 70  Caveolin1  Envelope protein   Densely Functionalized Macrocyclic Sesquiterpene Pyridine Alkaloids from Maytenus austroyunnanensis 期刊论文  OAI收割 JOURNAL OF NATURAL PRODUCTS, 2023, 页码: 11 作者:  Ji, Kai-Long;  Fan, Yao-Yue;  Gong, Qi;  Liu, Qun-Fang;  Cui, Ming-Jun   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 Diterpenoids from Euphorbia lactea and their anti-HIV-1 activity 期刊论文  OAI收割 PHYTOCHEMISTRY, 2023, 卷号: 213, 页码: 11 作者:  Zhao, Ye;  Hua, Chen;  Sha, Yi-ou;  Wu, Pei-Qian;  Liu, Qun-Fang   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 Euphorbia lactea Haw  Euphorbiaceae  Diterpenoid  Ingol  Ent -pimarane  Anti-HIV-1   Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18 作者:  Ren, Pengxuan;  Li, Hui;  Nie, Tianqing;  Jian, Xiaoqin;  Yu, Changyue   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 8, 页码: 3414-3424 作者:  Ji, Kailong;  Liu, Wei;  Yin, Weihang;  Kong, Xiangrong;  Xu, Honghong   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 Phychetins  Phyllanthus franchetianus  Structural elucidation  Total synthesis  Liver injury protection  Anti-inflammation