中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
采集方式
OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2023 [15]
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浏览/检索结果:
共15条,第1-10条
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发表日期:2023
专题:上海药物研究所
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Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:
Wang, Jingyi
;
Lin, Jianbang
;
Chen, Yefei
;
Liu, Jing
;
Zheng, Qiongping
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/01/16
Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 17
作者:
Zhang, Ranran
;
Wang, Pengyu
;
Wei, Bingyan
;
Chen, Liang
;
Song, Xiaomin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
ClpP agonists
Structure-activity relationship
Mitochondrial respiratory chain
Antileukemic therapy
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:
Zhang, Yong-mei
;
Zong, Hai-chao
;
Qi, Ying-bei
;
Chang, Liu-liu
;
Gao, Ya-nan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/12/08
Constructing N-Acyl/N-Sulfonyl Aza-Sulfur Derivatives from Amides/Sulfonamides and Thiophthalimides via Oxidant Regulation
期刊论文
OAI收割
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 32, 页码: 6018-6023
作者:
Li, Yazhou
;
Wang, Yongkun
;
Fang, Feifei
;
Zhang, Yu
;
Li, Chunpu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/10/17
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925
作者:
Zhou, Wei
;
Fang, Peng
;
Yu, Dongan
;
Ren, Hongyuan
;
You, Meng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 31, 页码: 17377-17388
作者:
Dou, Wei-Tao
;
Qiu, Peng
;
Shi, Yuanyuan
;
Zhu, Ling
;
Guo, Chen
  |  
收藏
  |  
浏览/下载:238/0
  |  
提交时间:2023/10/17
Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 24
作者:
Li, Xiao
;
Li, Fei
;
Ye, Fei
;
Guo, Haotian
;
Chen, Wentao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
Mitochondria-Targeting Small-Molecule NIR-II Fluorescent Probes for Imaging and Treatment of Tumor
期刊论文
OAI收割
ADVANCED THERAPEUTICS, 2023, 页码: 10
作者:
Li, Mingxun
;
Wu, Yibin
;
He, Chunfeng
;
Li, Xinxin
;
Tao, Ji
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
mitochondrial membrane potential
NIR-II imaging
photothermal therapy
small molecule probes
tumors