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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共742条，第1-10条 帮助

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Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869
作者:  Gu, Chenming;  Liu, Jiayuan;  Qian, Fei;  Yu, Wenchao;  Huang, Doudou
  |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:  Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin;  Liu, Lu
  |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:  Song, Zhaoxiang;  Lu, Dan;  Sun, Jun;  Ye, Yangliang;  Fang, Jiahui
  |  收藏  |  浏览/下载：31/0  |  提交时间：2024/01/16
GPR35  IBD  Lodoxamide  
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:  Zhu, Yueyue;  Liu, Bo;  Chen, Zonglong;  Wang, Xianyang;  Wang, Yujie
  |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L 期刊论文  OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:  Li, Xin;  Wu, Xiaowei;  Nie, Shenyou;  Zhao, Jidong;  Yao, Yuan
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/19
Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10
作者:  Li, Peizhuo;  Tian, Yucheng;  Shang, Qinghong;  Tang, Cailing;  Hou, Zeng
  |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17
Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPAR alpha agonists by in silico studies and biochemical evaluation 期刊论文  OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 16
作者:  Li, Yue;  Lv, Mengjia;  Shen, Meiling;  Gu, Xi;  Zhang, Li
  |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:  Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei
  |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17
Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:  Ren, Pengxuan;  Li, Hui;  Nie, Tianqing;  Jian, Xiaoqin;  Yu, Changyue
  |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17
TGR5 agonist inhibits intestinal epithelial cell apoptosis via cAMP/PKA/c-FLIP/JNK signaling pathway and ameliorates dextran sulfate sodium-induced ulcerative colitis 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1649-1664
作者:  Yang, Wen-ji;  Han, Fang-hui;  Gu, Yi-pei;  Qu, Hui;  Liu, Jia
  |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27