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浏览/检索结果: 共702条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 222, 页码: 11 作者:  Cheng, Yong -Jun;  Zhuang, Zhen;  Miao, Yu -Ling;  Song, Shan -Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 YCH2823  USP7 inhibitor  FT671  BCL6  mTOR inhibitor   Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism 期刊论文  OAI收割 LIVER INTERNATIONAL, 2024, 页码: 17 作者:  Hou, Aijun;  Xu, Xiaoding;  Zhang, Yu;  He, Hongxiu;  Feng, Yihan   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Drosha degradation  lipid metabolism  miRNA biogenesis  NAFLD  PRMT5   Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486 作者:  Chang, Qi;  Li, Jiayi;  Deng, Yue;  Zhou, Ruilin;  Wang, Bingwei   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/25 Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP) 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279 作者:  Zhou, Chenmao;  Hao, Xinyue;  Chen, Zhengyang;  Zhang, Runze;  Zhou, Qian   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/13 Speckle-type POZ protein (SPOP)  SPOP inhibitors  Clear cell renal cell carcinoma (ccRCC)  Structure-activityrelationship (SAR)   Role of F-box proteins in human upper gastrointestinal tumors 期刊论文  OAI收割 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2024, 卷号: 1879, 期号: 1, 页码: 16 作者:  Zhang, Che;  Pan, Guangzhao;  Qin, Jiang-Jiang   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/02/27 F-box protein  Upper gastrointestinal cancer  E3 ubiquitin ligase  Ubiquitin   The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/01/16 chimeric design  degradation System  PROTAC  targeted degradation technology  undruggable targets   Deubiquitylating Enzymes in Cancer and Immunity 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 页码: 37 作者:  Ren, Jiang;  Yu, Peng;  Liu, Sijia;  Li, Ran;  Niu, Xin   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 cancer  deubiquitylating enzymes (DUBs)  immunity  therapeutic approach   Genome-wide association study of hippocampal blood-oxygen-level-dependent-cerebral blood flow correlation in Chinese Han population 期刊论文  OAI收割 ISCIENCE, 2023, 卷号: 26, 期号: 10, 页码: 16 作者:  Xue, Hui;  Xu, Xiaojun;  Yan, Zhihan;  Cheng, Jingliang;  Zhang, Longjiang   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/11/29 Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17 作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14 作者:  Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Otilonium Bromide  Deubiquitinase  USP28  Selective inhibitor