中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [141]
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期刊论文 [241]
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Functional analysis of CYP71AV1 reveals the evolutionary landscape of artemisinin biosynthesis
期刊论文
OAI收割
FRONTIERS IN PLANT SCIENCE, 2024, 卷号: 15, 页码: 9
作者:
Chen, Fang-Yan
;
Mu, Qiu-Yan
;
Xu, Bing-Yi
;
Lei, Yu-Chen
;
Liu, Hui-Ying
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
artemisinin
Asteraceae sesquiterpene lactone
cytochrome P450 monooxygenases
amorpha-4
11-diene oxidase
germacrene A oxidase
molecular evolution
loss-of-function event
TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
TPN10475 alleviates concanavalin A-induced autoimmune hepatitis by limiting T cell development and function through inhibition of PI3K-AKT pathway
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 13
作者:
Wang, Chun
;
Han, Mengyao
;
Li, Xinhang
;
Lv, Jie
;
Zhuang, Wei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/01/16
AIH
T cell
Pro-inflammatory
IFN-gamma
PI3K-AKT
The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 123, 页码: 12
作者:
Xie, Ling
;
Lv, Jie
;
Saimaier, Kaidireya
;
Han, Sanxing
;
Han, Mengyao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
TPN10518
Th1/Th17 cells
AP1
Experimental autoimmune encephalomyelitis
Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11
作者:
Xu, Haiyu
;
Li, Shufen
;
Liu, Jiayuan
;
Cheng, Jinlong
;
Kang, Liping
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
COVID-19
traditional Chinese medicine
TCMT-NDRD
antivirus
anti-inflammation
Linalool: A ubiquitous floral volatile mediating the communication between plants and insects
期刊论文
OAI收割
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2023, 卷号: 61, 期号: 3, 页码: 538-549
作者:
Zhang, Ling
;
Su, Qia-Fan
;
Wang, Liang-Sheng
;
Lv, Meng-Wen
;
Hou, Yi-Xuan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/07
antagonist
floral volatiles
linalool
plant-insect interactions
pollination
Artemisinin derivative SM934 in the treatment of autoimmune and inflammatory diseases: therapeutic effects and molecular mechanisms
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 7
作者:
Tong, Xiao
;
Chen, Li
;
He, Shi-jun
;
Zuo, Jian-ping
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/09/30
artemisinin derivative
beta-aminoarteether maleate (SM934)
autoimmune and inflammatory diseases
T helper cells
macrophages
inflammatory cytokines
Artemisinin analog SM934 alleviates epithelial barrier dysfunction via inhibiting apoptosis and caspase-1-mediated pyroptosis in experimental colitis
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 18
作者:
Shao, Meijuan
;
Yan, Yuxi
;
Zhu, Fenghua
;
Yang, Xiaoqian
;
Qi, Qing
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/11/11
SM934
colitis
intestinal epithelial barrier
apoptosis
pyroptosis
NLRP3/caspase-1/GSDMD
MAPK/NF-kB
Synthesis and biological evaluation of artemisinin derivatives as potential MS agents
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 64, 页码: 5
作者:
Zhang, Yan
;
Lv, Jie
;
Zhang, Suqing
;
Yang, Hanxi
;
Shen, Jingshan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/08/16
Artemisinin derivatives
Multiple sclerosis
Th1/Th17
IFN-?/IL-17A
EAE
Novel process for selective separation of trace artemisitene from artemisinin by ammonium functional ionic liquids
期刊论文
OAI收割
AICHE JOURNAL, 2022, 页码: 13
作者:
Cao, Yingying
;
Tan, Xin
;
Zhan, Guoxiong
;
Li, Qiongguang
;
Wang, Hui
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/06/15
artemisinin/artemisitene
ionic liquids
multistage extraction
selective separation
pi-pi complexation