机构

• 上海药物研究所 [8]
• 过程工程研究所 [3]
• 武汉物理与数学研究所 [3]
• 上海应用物理研究所 [3]
• 上海生物化学与细胞生... [3]
• 合肥物质科学研究院 [3]
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采集方式

• OAI收割 [37]
• iSwitch采集 [2]

内容类型

• 期刊论文 [39]

发表日期

• 2024 [1]
• 2023 [1]
• 2022 [3]
• 2021 [2]
• 2020 [5]
• 2019 [6]
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学科主题

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浏览/检索结果: 共39条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486 作者:     |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/25 Structural analysis of the dual agonism at GLP-1R and GCGR 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 33, 页码: 12 作者:  Li, Yang;  Zhou, Qingtong;  Dai, Antao;  Zhao, Fenghui;  Chang, Rulue   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/07 glucagon-like peptide-1 receptor  glucagon receptor  cryo-electron microscopy  dual agonism   Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16 作者:  Chen, Zonglong;  Li, Jiayi;  Yang, Hong;  He, Yulong;  Shi, Qiongyu   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16 P300  Bromodomain inhibitors  CBP30  SBDD   Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文  OAI收割 PHARMACEUTICALS, 2022, 卷号: 15 作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei   |  收藏  |  浏览/下载：16/0  |  提交时间：2022/12/22 glucagon-like peptide-1  GLP-1 receptor agonist  functional protein design  molecular dynamics simulation  long-acting antihyperglycemic   Dependence of the rate-limiting steps in the dark-to-light transition of photosystem II on the lipidic environment of the reaction center 期刊论文  OAI收割 PHOTOSYNTHETICA, 2022, 卷号: 60, 期号: 1, 页码: 147-156 作者:  Magyar, M.;  Akhtar, P.;  Sipka, G.;  Han, W.;  LI, X.   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/07 closed state of PSII  conformational chang  dielectric relaxation  light-adapted state of PSII  light-induced changes  proteoliposomes   Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan 期刊论文  OAI收割 CELL RESEARCH, 2021 作者:  Ling, Shenglong;  Shi, Pan;  Liu, Sanling;  Meng, Xianyu;  Zhou, Yingxin   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/04/26 Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan 期刊论文  OAI收割 CELL RESEARCH, 2021, 页码: 12 作者:  Ling, Shenglong;  Shi, Pan;  Liu, Sanling;  Meng, Xianyu;  Zhou, Yingxin   |  收藏  |  浏览/下载：19/0  |  提交时间：2021/05/24 Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1 期刊论文  OAI收割 ELIFE, 2020, 卷号: 9 作者:  Sun, Demeng;  Liu, Sanling;  Li, Siyu;  Zhang, Mengge;  Yang, Fan   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/11/30 Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325 作者:  Chang, Rulue;  Zhang, Xin;  Qiao, Anna;  Dai, Antao;  Belousoff, Matthew J.   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24 glucagon receptor  glucagon-like peptide-1 receptor  dual agonist  cryo-electron microscopy  single particle analysis  structure-function  structural biology  peptide 15 (P15)  metabolic disorder  G protein?coupled receptor (GPCR)  glucagon  GLP-1 receptor   Structural basis of G(s) and G(i) recognition by the human glucagon receptor 期刊论文  OAI收割 SCIENCE, 2020, 卷号: 367, 期号: 6484, 页码: 1346-+ 作者:  Qiao, Anna;  Han, Shuo;  Li, Xinmei;  Li, Zhixin;  Zhao, Peishen   |  收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01