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浏览/检索结果: 共552条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Bialorastins A-F, highly oxygenated and polycyclic andrastin-type meroterpenoids with proangiogenic activity from the deep-sea cold-seep-derived fungus Penicillium bialowiezense CS-283 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 12 作者:  Yan, Li-Hong;  Li, Pei-Hai;  Li, Xiao-Ming;  Yang, Sui-Qun;  Liu, Ke-Chun   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/04/07 Cold-seep  Penicillium bialowiezense  Meroterpenoids  Proangiogenic activity   The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the antitumor efficacy of radiotherapy 期刊论文  OAI收割 THERANOSTICS, 2024, 卷号: 14, 期号: 3, 页码: 1195-1211 作者:  Zhang, Ying;  Akhil, Venu;  Seo, Ho Seong;  Park, Hae Ran;  Kim, Soo Hyun   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Cancer radiotherapy  immunogenic cell death  calreticulin  L-ASNase  reactive oxygen species  immune checkpoint inhibitor   Cryptotanshinone regulates gut microbiota and PI3K-AKT pathway in rats to alleviate CUMS induced depressive symptoms 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 169, 页码: 11 作者:  Bian, Li-hua;  Wang, Si-qi;  Li, Wen-jing;  Li, Jie;  Yin, Yi   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/18 Depression  Cryptotanshinone  16 S rDNA  Transcriptomics  PI3K-AKT pathway   Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches 期刊论文  OAI收割 BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17 作者:  Sultan, Rida;  Ahmed, Abrar;  Wei, Li;  Saeed, Hamid;  Islam, Muhammad   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/19 CDK2  ER+ Breast cancer  Molecular Docking  MM-GBSA  Molecular Dynamic Simulations  MTT assay  Moringa oleifera  Phytoconstituents  Chlorogenic acid   Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma 期刊论文  OAI收割 Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556 作者:  Yuan, Hong-Kai;  Li, Bo;  Wu, Leyun;  Wang, Xue-Ling;  Lv, Zhi-Ying   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/26 Active learning  Consensus labelling  Eye irritation  Serious eye damage  Structural alerts   Computational Experiments: A New Analysis Method for Cyber-Physical-Social Systems 期刊论文  OAI收割 IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS, 2023, 页码: 14 作者:  Xue, Xiao;  Shen, Yifan;  Yu, Xiangning;  Zhou, De-Yu;  Wang, Xiao   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/21 Cloud manufacturing service ecosystem (CMSE)  computational experiments  cyber-physical-social systems (CPSSs)  experiment analysis  experiment design   Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF) 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12 作者:  Wu, Xinyu;  Wang, Mingchen;  Cao, Yu;  Xu, Ying;  Yang, Ziqun   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/27 O-GlcNAcylation  O-GlcNAc transferase  High-throughput screening  Inhibitor   Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15 作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/10/17 Betulinic acid  ROR & gamma  Target identification  Rationale structure optimization  Anti-tumor effects  antagonists