中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Inulin-like polysaccharide ABWW may impede CCl
4
induced hepatic stellate cell activation through mediating the FAK/PI3K/AKT signaling pathway
in vitro
&
in vivo
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2024, 卷号: 326, 页码: 15
作者:
Dai, Xiaolan
;
Du, Zhenyun
;
Jin, Can
;
Tang, Bixi
;
Chen, Xia
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/19
Fructan
Hepatic fibrosis
Hepatic stellate cells
FAK/PI3K/AKT
SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Li, Wen-jing
;
Xie, Cheng-ying
;
Zhu, Xi
;
Tang, Jiao
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/02/19
SIBP-03
HER3
HER3-targeted therapy
neuregulin 1
EGFR
HER2
Identification of XAF1 as an endogenous AKT inhibitor
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 25
作者:
Chen, Min
;
Wang, Kangjunjie
;
Han, Ying
;
Yan, Shukun
;
Yuan, Huairui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
11-Ethoxyviburtinal improves chronic restraint stress-induced anxiety-like behaviors in gender-specific mice via PI3K/Akt and E-2/ER beta signaling pathways
期刊论文
OAI收割
PHYTOTHERAPY RESEARCH, 2023, 页码: 17
作者:
Lyu, Yan
;
Wei, Xiaojia
;
Yang, Xue
;
Li, Jiayuan
;
Wan, Guohui
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/09
11-ethoxyviburtinal
antagonists
anxiety disorder
estrogen receptor beta
PI3K-Akt signaling pathway
the male and female mice
Root-Extracted lignanamides from Limonium gmelinii (Willd.) Kuntze with a potential PTP1B inhibitory activity by regulating PI3K/AKT signaling pathway
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 9
作者:
Tuohongerbieke, Amanguli
;
Liu, Liu
;
Li, Jun
;
Xin, Xuelei
;
Aisa, Haji Akber
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
Limonium gmelinii (Willd
) Kuntze
Plumbaginaceae
Lignanamides
Protein tyrosine phosphatase 1B inhibitors
PI3K
AKT Signaling Pathway
Hypoglycemic effect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS
期刊论文
OAI收割
FOOD & FUNCTION, 2023, 卷号: 14, 期号: 17, 页码: 7869
作者:
Jiang, Sirong
;
Wang, Luya
;
Jia, Wenjing
;
Wu, Di
;
Wu, Li
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/01
Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases: Current Status, Trends, and Solutions
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 29
作者:
Huang, Jindi
;
Chen, Liye
;
Wu, Jiangxia
;
Ai, Daiqiao
;
Zhang, Ji-Quan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Vimentin binds to a novel tumor suppressor protein, GSPT1-238aa, encoded by circGSPT1 with a selective encoding priority to halt autophagy in gastric carcinoma
期刊论文
OAI收割
CANCER LETTERS, 2022, 卷号: 545, 页码: 14
作者:
Hu, Fan
;
Peng, Yin
;
Chang, Shanshan
;
Luo, Xiaonuan
;
Yuan, Yuan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/12/07
Circular RNAs
circGSPT1
Autophagy
Translation
Gastric cancer
Multi-omics analysis reveals the pathogenesis of db/db mice diabetic kidney disease and the treatment mechanisms of multi-bioactive compounds combination from Salvia miltiorrhiza
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 16
作者:
Xu, Zhuo
;
Xiang, Xiang
;
Su, Shulan
;
Zhu, Yue
;
Yan, Hui
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/13
multi-bioactive compounds combination
diabetic kidney disease
multi-omics
Salvia miltiorrhiza
PI3K/Akt/FoxO signaling pathways
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1