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• OAI收割 [160]

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浏览/检索结果: 共160条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/01/16 chimeric design  degradation System  PROTAC  targeted degradation technology  undruggable targets   Advances in biosynthesis of peptide drugs: Technology and industrialization 期刊论文  OAI收割 BIOTECHNOLOGY JOURNAL, 2023, 页码: 13 作者:  Wang, Jing;  Chen, Long;  Qin, Song;  Xie, Mingyuan;  Luo, Shi-Zhong   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/26 biosynthesis technology  industrialization  peptide drugs  peptide synthesis   ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292 作者:  Jiang, Lulu;  Liu, Sixiu;  Jia, Xinglong;  Gong, Qinting;  Wen, Xin   |  收藏  |  浏览/下载：30/0  |  提交时间：2024/01/16 Discovery of Potent and Selective CB2 Agonists Utilizing a Function-Based Computational Screening Protocol 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2023, 卷号: 14, 期号: 21, 页码: 3941-3958 作者:  Ge, Haixia;  Ji, Beihong;  Fang, Jiahui;  Wang, Jiayang;  Li, Jing   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/11 function-based ligand design  receptor-ligandbinding profile  CB1/CB2  structure-activityrelationship   'Passive' nanoparticles for organ-selective systemic delivery: design, mechanism and perspective 期刊论文  OAI收割 CHEMICAL SOCIETY REVIEWS, 2023 作者:  Fu, Liyi;  Zhang, Yang;  Farokhzad, Ryan A.;  Mendes, Barbara B.;  Conde, Joao   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/11/17 Nanovesicles loaded with a TGF-& beta; receptor 1 inhibitor overcome immune resistance to potentiate cancer immunotherapy 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18 作者:  Zhou, Mengxue;  Wang, Jiaxin;  Pan, Jiaxing;  Wang, Hui;  Huang, Lujia   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules 期刊论文  OAI收割 JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 42 作者:  Liu, Xiaohong;  Zhang, Wei;  Tong, Xiaochu;  Zhong, Feisheng;  Li, Zhaojun   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 De novo molecule design  Generative models  Deep learning  Virtual screening  Compound quality control   Discovery of Highly Potent and Selective Thyroid Hormone Receptor βAgonists for the Treatment of Nonalcoholic Steatohepatitis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3284-3300 作者:  Hu, Liuyu;  Gu, Yipei;  Liang, Ju;  Ning, Mengmeng;  Yang, Junli   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 Two dimensional measurements of receptor ligand interactions 期刊论文  OAI收割 FRONTIERS IN MOLECULAR BIOSCIENCES, 2023, 卷号: 10, 页码: 1154074 作者:  Zheng SJ(郑松杰);  Zou M(邹敏);  Shao YF(邵颖峰);  Wu, Huaping;  Wu, Helong   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/04/20 receptor ligand interaction  binding kinetics  kinetic on rate  kinetic off rate  binding affinity  two dimensional measuring methods   Ligand-modified nanocarriers for oral drug delivery: Challenges, rational design, and applications 期刊论文  OAI收割 JOURNAL OF CONTROLLED RELEASE, 2022, 卷号: 352, 页码: 813-832 作者:  Zhang, Yaqi;  Wang, Yaying;  Li, Xiang;  Nie, Di;  Liu, Chang   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 Ligand-modified nanocarriers  Transcytosis  Transporter  Active targeting  Oral drug delivery  Local drug delivery