机构

• 上海药物研究所 [11]
• 西北高原生物研究所 [9]
• 化学研究所 [3]
• 过程工程研究所 [3]
• 青岛生物能源与过程研... [3]
• 上海光学精密机械研究... [3]
• 更多

采集方式

• OAI收割 [40]
• iSwitch采集 [2]

内容类型

• 期刊论文 [42]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [3]
• 2021 [1]
• 2019 [1]
• 2018 [2]
• 更多

学科主题

• 半导体材料 [1]

筛选

浏览/检索结果: 共42条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of CZL-046 with an (S)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628 作者:  Chen, Zonglong;  Yang, Hong;  Zhang, Yan;  Lyu, Xiaodong;  Shi, Qiongyu   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/11/05 Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17 作者:  Zhu, Yueyue;  Liu, Bo;  Chen, Zonglong;  Wang, Xianyang;  Wang, Yujie   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/12/08 Toll -like receptor 2/6 agonists  PamCS  Structure-activity relationship  Lipopeptide  Immunostimulants   Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16 作者:  He, Yulong;  Li, Shunyi;  Zhu, Yueyue;  Wang, Yujie;  Chen, Yuqi   |  收藏  |  浏览/下载：78/0  |  提交时间：2023/10/17 Structure-activity relationship  FABP4 inhibitor  Biphenyl scaffold  Selectivity  Oral bioavailability  Anti-inflammation   Application of Pt loaded graphite felt in SO2-depolarized electrolyzer 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 2022, 卷号: 47, 期号: 74, 页码: 31575-31586 作者:  Ma, Xiaoshan;  Ding, Xifeng;  Sun, Xinliang;  Zhang, Ping;  Wang, Laijun   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/02/24 Hydrogen production  Hybrid sulfur (HyS) process  SO2-depolarized electrolysis (SDE)  Pt-loaded graphite felt  Three-dimensional anode   Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16 作者:  Chen, Zonglong;  Li, Jiayi;  Yang, Hong;  He, Yulong;  Shi, Qiongyu   |  收藏  |  浏览/下载：51/0  |  提交时间：2022/08/16 P300  Bromodomain inhibitors  CBP30  SBDD   Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15 作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu   |  收藏  |  浏览/下载：54/0  |  提交时间：2022/08/16 Epigenetics  p300  CBP  Bromodomain inhibitors  CCS1477   Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20 作者:  Gao, Dingding;  Jin, Nan;  Fu, Yixian;  Zhu, Yueyue;  Wang, Yujie   |  收藏  |  浏览/下载：47/0  |  提交时间：2021/06/11 STAT3 signaling pathway  Benzothiazole  Rational design  Antitumor activity  Molecular docking   Continued reassortment of avian H6 influenza viruses from Southern China, 2014-2016 期刊论文  OAI收割 TRANSBOUNDARY AND EMERGING DISEASES, 2019, 卷号: 66, 期号: 1, 页码: 592-598 作者:  Bi, Yuhai;  Shi, Weifeng;  Liu, William J.;  Gao, George F.;  Liu, Wenjun   |  收藏  |  浏览/下载：107/0  |  提交时间：2019/03/05 evolution  H6 subtype  low pathogenic avian influenza  molecular characterization  reassortment   Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306 作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong   |  收藏  |  浏览/下载：83/0  |  提交时间：2019/01/08 EGFR inhibitors  Pyrimidine derivatives  Mutant selective inhibitors  AZD9291  T790M   DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation 期刊论文  OAI收割 NATURE MEDICINE, 2018, 卷号: 24, 期号: 3, 页码: 262-+ 作者:  Xiao, Qian;  Wang, Wei-Jia;  Zheng, Yingxia;  Sahraei, Mahnaz;  Tang, Wenwen   |  收藏  |  浏览/下载：52/0  |  提交时间：2019/04/28 Intestinal Intraepithelial Lymphocytes  Wnt Signaling Pathway  Wnt/beta-catenin  Cancer-immunotherapy  Colorectal-cancer  Nk Cells  Therapy  Differentiation  Interleukin-15  Resistance