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浏览/检索结果: 共97条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Soluble epoxide hydrolase deficiency rescues heart failure with preserved ejection fraction by targeting cytochrome P450 2E1 期刊论文  OAI收割 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2026, 卷号: 210, 页码: 98-108 作者:  Zhang, Min;  Chen, Chen;  Liu, Xinxing;  Zhou, Zhou;  Li, Gen   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/01/28 Soluble epoxide hydrolase  Desuccinylation  Epoxyeicosatrienoic acids  Heart failure with preserved ejection fraction   Asymmetric Total Synthesis and Anti-Inflammatory Activity of Berbamine, Oxyacanthine, and Related Intermediates 期刊论文  OAI收割 JOURNAL OF NATURAL PRODUCTS, 2025, 页码: 13 作者:  Xiang, Li;  Qin, Jishan;  Kushatov, Temur;  Tursunov, Firdavsi;  Farmonov, Ozod   |  收藏  |  浏览/下载：0/0  |  提交时间：2026/01/28 Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11 作者:  Guma, Samuel Desta;  Song, Kang;  Sun, Haiguo;  Yang, Lei;  Zhou, Zhaoyin   |  收藏  |  浏览/下载：67/0  |  提交时间：2025/08/20 SARS-CoV-2  3CL(pro) inhibitors  Thioamide derivatives  Spiropyrrolidine derivatives  Nirmatrelvir  HCoV-OC43  Antiviral  Metabolic stability   An Asymmetric Reductive Amination Synthesis of Ritlecitinib Using (S)-α-Methylbenzylamine as Chiral Auxiliary 期刊论文  OAI收割 CHEMISTRY-A EUROPEAN JOURNAL, 2025, 页码: 10 作者:  Dong, Hongkun;  Bonku, Emmanuel Mintah;  Zhang, Yuxuan;  Yang, Xingbang;  Abduahadi, Safomuddin   |  收藏  |  浏览/下载：41/0  |  提交时间：2025/07/25 asymmetric reductive amination  chiral auxiliary  intramolecular amide formation  ritlecitinib  delta-lactam   Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826 作者:  Cheng, Yong;  Zheng, Wei;  Dong, Xinru;  Sun, Tengxiao;  Xu, Mengwei   |  收藏  |  浏览/下载：31/0  |  提交时间：2025/06/23 Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie   |  收藏  |  浏览/下载：28/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone   Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22 作者:  Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin   |  收藏  |  浏览/下载：63/0  |  提交时间：2024/12/11 SARS-CoV-2  3CL pro inhibitors  Peptidomimetics  Spiropyrrolidine derivatives   F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:  Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu   |  收藏  |  浏览/下载：62/0  |  提交时间：2025/02/28 Direct Reductive N-alkylation of Amines with Carboxylic Esters 期刊论文  OAI收割 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 7 作者:  Zhang, Yuxuan;  Bonku, Emmanuel Mintah;  Yang, Xingbang;  Zhu, Fuqiang;  Jiang, Xiangrui   |  收藏  |  浏览/下载：52/0  |  提交时间：2025/01/14 Direct reductive N-alkylation of amine  One-pot reaction  Grignard reagent  Amidation of ester  Cariprazine   Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 113, 页码: 5 作者:  Lu, Jie;  Cheng, Yan;  Zhang, Yumin;  Wang, Yi;  Xia, Bingqing   |  收藏  |  浏览/下载：45/0  |  提交时间：2025/02/28 Bisbenzylisoquinoline alkaloid  Oxyacanthine derivatives  SARS-CoV-2