中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
烟台海岸带研究所 [39]
海洋研究所 [35]
上海药物研究所 [13]
青岛生物能源与过程研... [4]
地质与地球物理研究所 [3]
大连化学物理研究所 [3]
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OAI收割 [111]
内容类型
期刊论文 [106]
CNKI期刊论文 [3]
专利 [1]
成果 [1]
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2025 [2]
2024 [21]
2023 [10]
2022 [21]
2021 [18]
2020 [10]
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Engineerin... [1]
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One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
De Novo siRNA nanoplatform with NIR-II imaging for treatment of carotid atherosclerotic plaques
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2025, 卷号: 503, 页码: 13
作者:
Gao, Jialu
;
Zhu, Hua
;
Cai, Huanhuan
;
Ding, Qihang
;
Xiong, Xiaoxing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/02/28
siRNA delivery
Atheromatous plaques
NIR-II imaging
Multifunctional nanoplatform
Epsin1/2
Asymmetric macrocyclization enabled by Rh(III)-catalyzed C-H activation: Enantioenriched macrocyclic inhibitor of Zika virus infection
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 11, 页码: 6
作者:
Chen, Chao
;
Yu, Wenwen
;
Huang, Guangen
;
Ren, Xuelian
;
Chen, Xiangli
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/09/26
C -H activation
Carboamidation
Enantioselective macrocyclization
Anti-Zika virus activity
Discovery of novel small molecules targeting hepatitis B virus core protein from marine natural products with HiBiT-based high-throughput screening
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4914-4933
作者:
Huang, Chao
;
Jin, Yang
;
Fu, Panpan
;
Hu, Kongying
;
Wang, Mengxue
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/01/06
Anti-HBV
HBV core protein
Core protein assembly modulators
Marine natural products
HiBiT
Lead compound
Naamidine J derivative
Bioactivity-driven synthesis
Evaluation of monoamine oxidase B fluctuation in liver fibrosis cell and mice models via a specificity fluorescent probe
期刊论文
OAI收割
SENSORS AND ACTUATORS B-CHEMICAL, 2024, 卷号: 417, 页码: 8
作者:
Sun, Mingzhao
;
Huang, Yan
;
Sun, Xiao
;
Fu, Lili
;
Wang, Lingxiao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/10/24
Liver fibrosis
Monoamine oxidase B
Fluorescence probe
In -situ monitoring
Early diagnosis
Macroalgal fossil
Longfengshania
from the Tonian Shiwangzhuang and Jiuliqiao formations in western Shandong and northern Anhui, North China
期刊论文
OAI收割
PALAEOWORLD, 2024, 卷号: 33, 期号: 5, 页码: 1153-1169
作者:
Li, Guang-Jin
;
Chen, Lei
;
Pang, Ke
;
Tang, Qing
;
Wu, Cheng-Xi
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/03/28
North China
Tonian
Shiwangzhuang Formation
Jiuliqiao Formation
Longfengshania
Comparative assessment of the intragenomic variations of dinoflagellate
Tripos
species through single-cell sequencing
期刊论文
OAI收割
MARINE POLLUTION BULLETIN, 2024, 卷号: 206, 页码: 12
作者:
Huang, Xianliang
;
Li, Yingchao
;
Du, Haina
;
Chen, Nansheng
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/09/02
Tripos
Single cell analysis
Intra-genomic variations (IGVs)
Molecular diversity
Metabarcoding
A Nanofluorescent Probe for Evaluating the Fluctuation of Aminopeptidase N in Nonalcoholic Fatty Liver Disease and Hepatic Fibrosis
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2024, 卷号: 96, 期号: 36, 页码: 14639-14649
作者:
Sun, Xiao
;
Wang, Xinlei
;
Fu, Lili
;
Wang, Xiaoyan
;
Chen, Lingxin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/10/24
Anti-HBV Activities of Cembranoids from the South China Sea Soft Coral
Sinularia pedunculata
and Their Structure Activity Relationship
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2024, 页码: 8
作者:
Huang, Chao
;
Jin, Yang
;
Sun, Ruo-Nan
;
Hu, Kong-Ying
;
Yao, Li-Gong
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2024/08/22
Hepatitis B Virus
cembranoid
anti-HBV activity
structure-activity relationship
ENI/Xp enhancer/promoter
In situ reprogramming of cardiac fibroblasts into cardiomyocytes in mouse heart with chemicals
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Chen, Zi-yang
;
Ji, Si-jia
;
Huang, Chen-wen
;
Tu, Wan-zhi
;
Ren, Xin-yue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
cardiac transdifferentiation
in situ transdifferentiation
small molecules
cardiomyocytes
fibroblasts
in vivo transdifferentiation