中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [26]
化学研究所 [4]
半导体研究所 [1]
烟台海岸带研究所 [1]
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OAI收割 [32]
内容类型
期刊论文 [32]
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2024 [2]
2023 [4]
2022 [1]
2021 [1]
2020 [7]
2019 [1]
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学科主题
半导体物理 [1]
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浏览/检索结果:
共32条,第1-10条
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Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma
期刊论文
OAI收割
HAEMATOLOGICA, 2024, 卷号: 109, 期号: 4, 页码: 1206-1219
作者:
Chen, Gege
;
Gao, Xuejie
;
Jia, Xinyan
;
Wang, Yingcong
;
Xu, Li
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/05/07
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma
期刊论文
OAI收割
LEUKEMIA, 2023, 页码: 4
作者:
Xu, Li
;
Wang, Yingcong
;
Wang, Guanli
;
Guo, Shushan
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/10/17
A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 2, 页码: 215
作者:
Zhang Bibo
;
Li Bo
;
Xie Yongsheng
;
Chang Shuaikang
;
Xu Zhijian
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/07/18
DCZ0358
apoptosis
cell cycle arrest
multiple myeloma
JAK2/STAT3 pathway
Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma
期刊论文
OAI收割
Journal of Biomedical Science, 2022, 卷号: 29, 期号: 1
作者:
Xie,Yongsheng
;
Wang,Yingcong
;
Xu,Zhijian
;
Lu,Yumeng
;
Song,Dongliang
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15
4-Hydroxysalicylanilid
Ribonucleotide reductase
Deoxyribonucleotides
DNA damage repair
Multiple myeloma
Antimicrobial Defensin and DNA Traps in Manila Clam Ruditapes philippinarum: Implications for Their Roles in Immune Responses
期刊论文
OAI收割
FRONTIERS IN MARINE SCIENCE, 2021, 卷号: 8, 页码: 10
作者:
Han, Yijing
;
Hu, Gege
;
Chen, Yuying
;
Chen, Lizhu
;
Yu, Daode
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/10/21
Ruditapes philippinarum
defensin
extracellular traps
antimicrobial effect
membrane permeabilization
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
OAI收割
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
OAI收割
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway