机构

• 上海药物研究所 [59]
• 昆明植物研究所 [55]
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• 近代物理研究所 [28]
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• OAI收割 [536]
• iSwitch采集 [10]

内容类型

• 期刊论文 [546]

发表日期

• 2025 [2]
• 2024 [20]
• 2023 [21]
• 2022 [41]
• 2021 [58]
• 2020 [62]
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学科主题

• Plant Sci... [13]
• Biochemist... [7]
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筛选

浏览/检索结果: 共546条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8 作者:  Wang, Shi-hang;  Zeng, Yue;  Yang, Hao;  Tian, Si-yuan;  Zhou, Yong-qi   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/07/25 N-methyl-D-aspartate receptors  GluN1/GluN3A  ligand-based virtual screening  scaffold hopping  deep learning  GeminiMol   One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18 作者:  Li, Huaxuan;  Yang, Hong;  Liu, Li;  Zheng, Jiahong;  Shi, Qiongyu   |  收藏  |  浏览/下载：36/0  |  提交时间：2024/12/11 Protein arginine methyltransferase 5  Nucleoside derivatives  Piperazine  Metabolic stability  Symmetric dimethylarginines   Emerging Pollutants 期刊论文  OAI收割 PROGRESS IN CHEMISTRY, 2024, 卷号: 36, 期号: 11, 页码: 1607-1784 作者:  Wang, Yawei;  Zhang, Qiurui;  Yu, Nanyang;  Wang, Yuan;  Wei, Si   |  收藏  |  浏览/下载：41/0  |  提交时间：2025/04/03 emerging pollutants  occurrence level  environmental behavior  ecological risks  control strategies   Discovery of CZL-046 with an (S)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628 作者:  Chen, Zonglong;  Yang, Hong;  Zhang, Yan;  Lyu, Xiaodong;  Shi, Qiongyu   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/11/05 Transcriptomic decoding of regional cortical vulnerability to major depressive disorder 期刊论文  OAI收割 COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12 作者:  Zhu, Jiajia;  Chen, Xiao;  Lu, Bin;  Li, Xue-Ying;  Wang, Zi-Han   |  收藏  |  浏览/下载：45/0  |  提交时间：2024/09/10 Efficacy, safety and biomarkers of SG001 for patients with previously treated recurrent or metastatic cervical cancer: an open-label, multicenter, phase Ib trial 期刊论文  OAI收割 CANCER COMMUNICATIONS, 2024 作者:  Zuo, Jing;  Duan, Wei;  Zhao, Mingxuan;  Chen, Zhendong;  Lin, Jie   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/11/22 Targeting CCL2-CCR2 signaling pathway alleviates macrophage dysfunction in COPD via PI3K-AKT axis 期刊论文  OAI收割 CELL COMMUNICATION AND SIGNALING, 2024, 卷号: 22, 期号: 1, 页码: 19 作者:  Dong, Yue;  Dong, Ying;  Zhu, Chengyue;  Yang, Lan;  Wang, Hanlin   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/08/22 Chronic obstructive pulmonary disease  C-C motif chemokine ligand 2  C-C chemokine receptor type 2  Bronchial epithelial cells  Macrophage   FXR activation remodels hepatic and intestinal transcriptional landscapes in metabolic dysfunction-associated steatohepatitis 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 15 作者:  Wen, Ying-quan;  Zou, Zi-yuan;  Zhao, Guan-guan;  Zhang, Meng-jiao;  Zhang, Yong-xin   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/08/22 MASLD/MASH  FXR  transcriptome  gut-liver axis  agonist   Trametinib, an anti-tumor drug, promotes oligodendrocytes generation and myelin formation 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13 作者:  Yang, Ying;  Suo, Na;  Cui, Shi-hao;  Wu, Xuan;  Ren, Xin-yue   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/07/12 oligodendrocyte differentiation  oligodendrocyte progenitor cell  remyelination  trametinib  MEK inhibitor  MEK/ERK pathway   Cross-ancestry genome-wide association studies of brain imaging phenotypes 期刊论文  OAI收割 NATURE GENETICS, 2024, 页码: 31 作者:  Fu, Jilian;  Zhang, Quan;  Wang, Jianhua;  Wang, Meiyun;  Zhang, Bing   |  收藏  |  浏览/下载：57/0  |  提交时间：2024/06/29