中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
地理科学与资源研究所 [4]
植物研究所 [2]
上海硅酸盐研究所 [2]
计算技术研究所 [1]
数学与系统科学研究院 [1]
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OAI收割 [19]
iSwitch采集 [1]
内容类型
期刊论文 [20]
发表日期
2025 [1]
2024 [3]
2022 [2]
2021 [3]
2020 [2]
2019 [3]
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学科主题
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Design of Selective BRD4 Inhibitors for the Treatment of Autosomal Dominant Polycystic Kidney Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 18
作者:
Yang, Yueyue
;
Liu, Hongli
;
Yuan, Haoxing
;
Lyu, Kaikai
;
Zhong, Haiyang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:
Wang, Yingying
;
Zhang, Youping
;
Luo, Hao
;
Wei, Wei
;
Liu, Wanting
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Ubiquitin-specific protease 2
KRAS
Gambogic acid
Multiple myeloma
Degradation
Ubiquitination
Allosteric pocket
Deubiquitination
Predicting transcriptional responses to novel chemical perturbations using deep generative model for drug discovery
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 19
作者:
Qi, Xiaoning
;
Zhao, Lianhe
;
Tian, Chenyu
;
Li, Yueyue
;
Chen, Zhen-Lin
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/12/06
Design, synthesis and structure-activity relationship of 1,8-naphthalimide derivatives as highly potent hCYP1B1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 8
作者:
Wei, Yueyue
;
Xiong, Yuan
;
Liao, Qingyi
;
Yang, Ya
;
Tian, Tian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/07/12
8-naphthalimide
Structure -activity relationships (SAR)
Paclitaxel (PTX) resistance
Molecular docking
Design and development of a novel series of oral bivalent BET inhibitors with potent anticancer activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 13
作者:
Luo, Menglan
;
Wu, Qian
;
Yang, Yueyue
;
Sun, Lin
;
Huan, Xiajuan
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/08/30
BET inhibitor
BRD4
Bivalent inhibitor
Anticancer
Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 1943-1962
作者:
Wang, Qi
;
Tang, Bixi
;
Sun, Dandan
;
Dong, Ying
;
Ji, Yinchun
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/08/16
Idiopathic pulmonary fibrosis
Discoidin domain receptor
Kinase
Inhibitor
Docking
Response of Growing Season Gross Primary Production to El Nino in Different Phases of the Pacific Decadal Oscillation over Eastern China Based on Bayesian Model Averaging
期刊论文
OAI收割
ADVANCES IN ATMOSPHERIC SCIENCES, 2021, 卷号: 38, 期号: 9, 页码: 1580-1595
作者:
Li, Yueyue
;
Dan, Li
;
Peng, Jing
;
Wang, Junbang
;
Yang, Fuqiang
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/11/05
East China
Bayesian model averaging
Gross primary production
El Nino
Pacific Decadal Oscillation
Monsoon rainfall
Response of Growing Season Gross Primary Production to El Nino in Different Phases of the Pacific Decadal Oscillation over Eastern China Based on Bayesian Model Averaging
期刊论文
OAI收割
ADVANCES IN ATMOSPHERIC SCIENCES, 2021, 卷号: 38, 期号: 9, 页码: 1580-1595
作者:
Li, Yueyue
;
Dan, Li
;
Peng, Jing
;
Wang, Junbang
;
Yang, Fuqiang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/05
East China
Bayesian model averaging
Gross primary production
El Nino
Pacific Decadal Oscillation
Monsoon rainfall
Discovery of a series of 1H-pyrrolo[2,3-b]pyridine compounds as potent TNIK inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 33, 页码: 127749
作者:
Yang, Bowen
;
Wu, Qian
;
Huan, Xiajuan
;
Wang, Yingqing
;
Sun, Yin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/03/21
TNIK inhibitor
1H-pyrrolo[2,3-b]pyridine
IL-2 secretion inhibitory
Investigation of the remote acyl group participation in glycosylation from conformational perspectives by using trichloroacetimidate as the acetyl surrogate
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 13, 页码: 1606-1615
作者:
Xu, Ke
;
Man, Qingmin
;
Zhang, Yang
;
Guo, Jia
;
Liu, Yichu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24