机构

• 长春应用化学研究所 [7]
• 上海生物化学与细胞生... [4]
• 上海药物研究所 [2]
• 自动化研究所 [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [15]

内容类型

• 期刊论文 [15]

发表日期

• 2024 [1]
• 2021 [1]
• 2018 [2]
• 2016 [1]
• 2015 [4]
• 2014 [2]
• 更多

学科主题

• Biotechnol... [1]
• Oncology [1]

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794 作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu   |  收藏  |  浏览/下载：51/0  |  提交时间：2021/05/24 Tyrosine kinase  Covalent FGFR inhibitors  Virtual screening  Pyrazolo[3,4-d] pyridazinone  Structure-activity relationships  Antitumor efficacy   GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostate cancer stem-like cells in vitro and in vivo 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 3, 页码: 405-414 作者:  Ying, Chang;  Xiao, Bo-duan;  Qin, Yun;  Wang, Bin-rong;  Liu, Xin-yuan   |  收藏  |  浏览/下载：53/0  |  提交时间：2019/04/28 Potent Antitumor-activity  Colorectal-cancer  Gene  Identification  Heterogeneity  Plasticity  Resistance  Xenograft  Promoter  Efficacy   Adenovirus armed with VGLL4 selectively kills hepatocellular carcinoma with G2/M phase arrest and apoptosis promotion 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 4, 页码: 2758-2763 作者:  Xie, Wenjie;  Hao, Jiali;  Liu, Xinyuan;  Zhang, Kangjian;  Liu, Xinyuan   |  收藏  |  浏览/下载：16/0  |  提交时间：2019/04/28 Oncolytic Adenovirus  Cancer Virotherapy  Antitumor Efficacy  Gastric-cancer  Lung-cancer  Therapy  Potency  Protein   The modulation of tumor vessel permeability by thalidomide and its impacts on different types of targeted drug delivery systems in a sarcoma mouse model 期刊论文  OAI收割 JOURNAL OF CONTROLLED RELEASE, 2016, 卷号: 238, 页码: 186-196 作者:  Wang, Dan;  Fu, Jijun;  Shi, Yujie;  Peng, Dong;  Yuan, Lan   |  收藏  |  浏览/下载：45/0  |  提交时间：2016/12/26 Targeted Drug Delivery Systems  Animal Model Of Epr Effect  Tumor Vessel Permeability  Thalidomide  Antitumor Efficacy  Distribution   miRNA oligonucleotide and sponge for miRNA-21 inhibition mediated by PEI-PLL in breast cancer therapy 期刊论文  OAI收割 acta biomaterialia, 2015, 卷号: 25, 页码: 184-193 作者:  Li,Mingqiang;  Tang,Zhaohui;  Zhang,Yu;  Lv,Shixian;  Li,Quanshun 收藏  |  浏览/下载：114/0  |  提交时间：2016/05/04 CELL LUNG-CANCER  DRUG-DELIVERY  IN-VIVO  CO-DELIVERY  ANTITUMOR EFFICACY  TUMOR-GROWTH  DOXORUBICIN  THERAPY  PACLITAXEL  INHIBITION   cRGD targeted and charge conversion-controlled release micelles for doxorubicin delivery 期刊论文  OAI收割 rsc advances, 2015, 卷号: 5, 期号: 29, 页码: 22957-22964 作者:  Guan,Xingang;  Hu,Xiuli;  Li,Zhizhong;  Zhang,Hong;  Xie,Zhigang 收藏  |  浏览/下载：17/0  |  提交时间：2016/05/20 ENHANCED ANTITUMOR EFFICACY  DRUG-DELIVERY  CANCER-THERAPY  TRIBLOCK COPOLYMER  POLYMERIC MICELLES  TUMOR VASCULATURE  NANOPARTICLES  THERAPEUTICS  CISPLATIN  PRODRUG   Targeted delivery of cisplatin by LHRH-peptide conjugated dextran nanoparticles suppresses breast cancer growth and metastasis 期刊论文  OAI收割 acta biomaterialia, 2015, 卷号: 18, 期号: 12, 页码: 132-143 作者:  Li,Mingqiang;  Tang,Zhaohui;  Zhang,Yu;  Lv,Shixian;  Li,Quanshun 收藏  |  浏览/下载：49/0  |  提交时间：2016/05/04 CELL LUNG-CANCER  DRUG-DELIVERY  IN-VIVO  CO-DELIVERY  ANTITUMOR EFFICACY  TUMOR-GROWTH  DOXORUBICIN  THERAPY  PACLITAXEL  INHIBITION   Pharmacokinetics, biodistribution and in vivo efficacy of cisplatin loaded poly(L-glutamic acid)-g-methoxy poly(ethylene glycol) complex nanoparticles for tumor therapy 期刊论文  OAI收割 journal of controlled release, 2015, 卷号: 205, 期号: 10, 页码: 89-97 作者:  Yu,Haiyang;  Tang,Zhaohui;  Zhang,Dawei;  Song,Wantong;  Zhanga,Ying 收藏  |  浏览/下载：43/0  |  提交时间：2016/05/03 INCORPORATED POLYMERIC MICELLES  PLGA-MPEG NANOPARTICLES  DRUG-DELIVERY  ENHANCED PERMEABILITY  ANTITUMOR EFFICACY  TARGETED DELIVERY  ANTICANCER DRUG  SOLID TUMORS  CO-DELIVERY  CANCER   Cyclic RGD targeting nanoparticles with pH sensitive polymer-drug conjugates for effective treatment of melanoma 期刊论文  OAI收割 rsc advances, 2014, 卷号: 4, 期号: 98, 页码: 55187-88194 Guan, Xingang; Hu, Xiuli; Liu, Shi; Huang,Yubin; Jing,Xiabin; Xie,Zhigang 收藏  |  浏览/下载：25/0  |  提交时间：2015/10/19 ANTITUMOR EFFICACY  DELIVERY SYSTEM  CANCER-THERAPY  TUMOR VASCULATURE  ANTICANCER DRUGS  MICELLES  MICROENVIRONMENT  BIODISTRIBUTION  THERAPEUTICS  PRODRUG