中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [50]
大连化学物理研究所 [5]
昆明植物研究所 [5]
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西北高原生物研究所 [3]
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OAI收割 [89]
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期刊论文 [87]
学位论文 [2]
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2024 [5]
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2020 [6]
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Oncology [3]
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浏览/检索结果:
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Rebalancing the inflammatory trajectory from inflammatory bowel disease to colitis-associated colorectal cancer via artemisinin-based multitarget therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2026, 页码: 14
作者:
He, Shi-jun
;
Tang, Mei-lin
;
Chen, Li
;
Zuo, Jian-ping
;
Xu, Han-chen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/04/01
inflammatory bowel disease
colorectal cancer
artemisinins
anti-inflammatory therapeutics
immune modulation
carcinogenesis
Endoplasmic reticulum-targeted strategies for programmed cell death in cancer therapy: Approaches and prospects
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2025, 卷号: 385, 页码: 17
作者:
Liang, Li
;
Zhu, Zhu
;
Jiang, Xiaohe
;
Tang, Yan
;
Li, Jiaxin
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/12/04
Endoplasmic reticulum
Targeted drug delivery
Nanoparticle
Programmed cell death
Anti-cancer therapy
Novel antimicrobial peptide ECCT from Chinese water snake is a potential candidate for the treatment of
Helicobacter
pylori
infection and gastric cancer
期刊论文
OAI收割
MICROBIAL PATHOGENESIS, 2025, 卷号: 206, 页码: 13
作者:
Qiu, Jie
;
Shi, Wenzhuang
;
Qian, Zhenghai
;
Zhang, Pengyu
;
Li, Shuangyu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/10/14
Enhydris chinensis
Cathelicidin
Anti-H. pylori
Anti-Inflammation
Anti-Gastric cancer
Synthesis and Evaluation of Trehalose-Based Mertansine Warheads for Bacillus Calmette-Guérin Delivery of Anticancer Agents
期刊论文
OAI收割
CHEMBIOCHEM, 2025, 页码: 10
作者:
Grimmeisen, Michael
;
Wang, Xuan
;
Weldle, Melissa
;
Sartory, Kerstin
;
Benkhelifa, Sara
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/12/04
antigen 85 complex
anti cancer agents
bladder cancer
delivery
mertansine
mycobacteria
trehalose
An updated patent review of TEAD modulators (2022-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2025, 页码: 27
作者:
Xu, Dounan
;
Zhong, Jiahuan
;
Zeng, Yuhan
;
Zhang, Xianhui
;
Wang, Chengyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/12/04
Hippo signaling pathway
transcriptional enhanced associated domain (TEAD)
modulators
anti-cancer drugs
degraders
combination therapy
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 17
作者:
Zhuang, Zhen
;
Miao, Yu-Ling
;
Song, Shan-Shan
;
Leng, Guang-Tong
;
Zhang, Xiao-Fei
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2024/09/26
USP7 inhibitor
Structure-activity relationships
Anti-cancer
pyrrolo[2,3-d]pyrimidin-4-one
Design, Synthesis, and Biological Evaluation of HDAC Inhibitors Containing Natural Product-Inspired
N
-Linked 2-Acetylpyrrole Cap
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 19, 页码: 26
作者:
Zhang, Han
;
Shen, Qianqian
;
Hu, Zhu
;
Wu, Pei-Qian
;
Chen, Yi
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2024/11/26
HDAC inhibitors
anti-cancer activity
natural products
pyrrole derivatives
molecular docking
molecular dynamics simulation
Resveratrol enhances the antiliver cancer effect of cisplatin by targeting the cell membrane protein PLA2
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2024, 卷号: 14
作者:
Gao, Yu
;
Yang, Zhanyi
;
Bajpai, Akhilesh Kumar
;
Wang, Wenben
;
Zhang, Liyuan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/11/20
combination therapy
resveratrol
cisplatin
anti-liver cancer mechanism
cell membrane
PLA2
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3-
d
]pyrimidin-7-one-based SOS1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9
作者:
Wang, Kun
;
Zhou, Zehui
;
Ma, Xinyi
;
Xu, Jiahang
;
Xu, Wangyang
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2024/07/12
SOS1
KRAS mutation
PROTAC
Anti-cancer activity