中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [22]
金属研究所 [12]
昆明植物研究所 [7]
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期刊论文 [62]
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Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity
期刊论文
OAI收割
MOLECULES, 2022, 卷号: 27, 期号: 18, 页码: 22
作者:
Ma, Longjun
;
Zhou, Yan
;
Yang, Dehua
;
Wang, Ming-Wei
;
Lu, Wei
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/11/11
androgen receptor
antagonist
enzalutamide
hydantoin analogs
antiproliferative
Sheep tail fat inhibits the proliferation of non-small-cell lung cancer cells in vitro and in vivo
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Xu, Changzhi
;
Zhang, Lanlan
;
He, Huimin
;
Liu, Xiaoyi
;
Pei, Xinxin
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2022/12/23
sheep tail fat
non-small-cell lung cancer
heptadecanoic acid
antiproliferative effect
Akt
S6K signaling pathway
Clerodenoids A-F: C-ring Aromatized and/or Rearranged Abietane Diterpenoids from Clerodendrum chinense var. simplex
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2021, 页码: 7
作者:
Qi, Jingjing
;
Zhang, Yan
;
Liu, Qunfang
;
Liu, Hongchun
;
Fan, Yaoyue
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Clerodendrum chinense
Natural products
Diterpenoids
Structural elucidation
Antiproliferative activities
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:
Xiao, Xuanzheng
;
Lai, Mengzhen
;
Song, Zilan
;
Geng, Meiyu
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/05/24
KRAS
Covalent inhibitor
Pyridopyrimidinone
Antiproliferative effect
Scaffold hopping
Divalent tranylcypromine derivative as lysine-specific demethylase 1 inhibitor
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2021, 页码: 8
作者:
Sun, Yin
;
Li, Na
;
Su, Mingbo
;
Wang, Xiaowen
;
Zhao, Dongmei
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/05/24
Divalent tranylcypromine
LSD1 inhibitor
MV4-11 antiproliferative activity
CD86 mRNA expression
Linker
Selectivity
Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4
作者:
Xiang, Hao-Yue
;
Chen, Jian-Yang
;
Huan, Xia-Juan
;
Chen, Yi
;
Gao, Zhao-bing
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Antiproliferative
Cancer
PARP inhibitors
Pyrrolo[12-b]pyridazine
Design, synthesis and anti-tumor activities of carbamate derivatives of cinobufagin
期刊论文
OAI收割
STEROIDS, 2020, 卷号: 164, 页码: 11
作者:
Zhou, Yang
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
;
Lei, Min
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
Cardiac glycosides
Cinobufagin
Natural product
Cytotoxicity
Antiproliferative activities
Bungsteroid A: One Unusual C 34 Pentacyclic Steroid Analogue from Zanthoxylum bungeanum Maxim
期刊论文
OAI收割
the Journal of Organic Chemistry, 2020, 卷号: 85, 期号: 16, 页码: 10806−10812
作者:
Meng XH(孟宪华)
;
Chai T(柴甜)
;
Shi YP(师彦平)
;
Yang JL(杨军丽)
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/11/16
Zanthoxylum bungeanum Maxim
quantum-chemical 13C NMR
ECD
antiproliferative effect
steroid
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo [2,1-f] [1,2,4] triazine derivatives
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 12, 页码: 4
作者:
Xiang, Hao-Yue
;
Chen, Yan-Hong
;
Wang, Yi
;
Zhang, Xi
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Antiproliferative
Cancer
Therapy
PI3K inhibitors
Pyrrolo [2,1-f][1,2,4] triazine
Kinase
Antiproliferative abietane quinone diterpenoids from the roots of Salvia deserta
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 104, 期号: 11, 页码: 1-12
作者:
Zheng, XF (Zheng, Xiaofeng)[ 1 ]
;
Kadir, A (Kadir, Abdukriem)[ 1,2 ]
;
Zheng, GJ (Zheng, Guijuan)[ 1 ]
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/01/05
Salvia deserta Schang (Lamiaceae)
Abietane quinone diterpenoids
Calculated C-13 NMR-DP4+analysis
Mo-2(OAc)(4)-induced ECD
Antiproliferative activity