中国科学院机构知识库网格系统: 检索

Characterization of and isolation methods for plant leaf nanovesicles and small extracellular vesicles 期刊论文 OAI收割
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 29
作者: Liu, Yuan; Wu, Sherry; Koo, Yeonjong; Yang, An; Dai, Yanwan

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收藏 | 浏览/下载：44/0 | 提交时间：2022/03/01

Cancer cell uptake Isolation method Leaf nanovesicles Plant sEVs Plant sEV and nanovesicle proteome Therapeutic delivery

A label-free quantification method for measuring graphene oxide in biological samples 期刊论文 OAI收割
ANALYTICA CHIMICA ACTA, 2019, 卷号: 1079, 页码: 103-110
作者: Xin, Yan; Wan, Bin

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收藏 | 浏览/下载：24/0 | 提交时间：2020/09/10

Graphene oxide Gel electrophoresis Exposure quantification Cell uptake

食用蔬菜能吸收和积累微塑料 期刊论文 OAI收割
科学通报, 2019, 卷号: 64, 期号: 9, 页码: 928-934
作者: 李连祯; 周倩; 尹娜; 涂晨; 骆永明

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收藏 | 浏览/下载：143/0 | 提交时间：2020/06/17

微塑料生菜聚苯乙烯微球吸收积累健康风险 microplastics lettuce polystyrene microbeads uptake accumulation human health risk Microplastic (MP, 100 nm-5 mm) may present an attributable risk to ecosystem and human health, and its pollution has become a global environmental concern. Despite a wealth of information on the accumulation of MPs in aquatic species, there is no information on the uptake and accumulation of MPs by higher plants. Terrestrial edible plants are directly exposed to MPs when agricultural soil was applied with organic manure, sewage sludge as fertilizer or plastic mulching. In this paper, the uptake of two sizes of polystyrene (PS) microbeads (0.2 and 1.0 mum) and then their distribution and migration in an edible plant lettuce were firstly investigated based on laboratory experiments. We used fluorescent markers to track PS microbeads in plant tissues and found fluorescence to be a sensitive and reliable detection method. Sections from untreated control lettuce showed no autofluorescence. When roots were treated with fluorescently labeled PS microbeads, the microbeads could be identified by its fluorescence. Our main study investigated the uptake of 0.2 mum beads, as few luminescence signals were observed in lettuce roots for 1.0 mum beads in our experiment. We observed that 0.2 mum fluorescent microbeads were extracellularly trapped in the root cap mucilage (which is a highly hydrated polysaccharide) and a dark green tip (which was typical of lettuce roots exposed to label PS beads) was usually visible to the naked eye. Confocal images revealed that the PS luminescence signals were mainly located in the vascular system and on the cell walls of the cortex tissue of the roots, indicated that the beads passed through the intercellular space via the apoplastic transport system. Once inside the central cylinder, the 0.2 mum PS beads were transferred from the roots to the stems and leaves via the vascular system following the transpiration stream. We also observed that the PS beads adhered to one another and self-assembled systematically into grape-like and (chain) string-like clusters in the intercellular space of the root and stem vascular tissue of lettuce plant. In contrast to the root and stem, PS beads were dispersed in the leaf tissue. Here, for the first time we provide evidence of the adherence, uptake, accumulation, and translocation of submicrometer MPs within an edible plant. Our findings highlight the previously underappreciated human exposure pathway to MPs through the consumption of contaminated crops and emphasize the need for new management strategies to control the release of MPs waste products into the terrestrial environment. Ultimately, the potential impacts of low range sized MPs on food safety of crop plants and human health need to be urgently considered.

Improved Biocompatibility of Black Phosphorus Nanosheets by Chemical Modification 期刊论文 OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 卷号: 56, 期号: 46, 页码: 14488-14493
作者: Xia, Tian; Shi, Jianbo; Hu, Ligang; Zhou, Wenhua; Gao, Jiejun

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收藏 | 浏览/下载：40/0 | 提交时间：2018/07/26

Biocompatibility Black Phosphorus Cell Uptake Inflammations Surface Modification

Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity 期刊论文 OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 11, 页码: 2488-2492
作者: Zhang, Renshuai; Song, Lairong; Jiang, Bo; Wang, Lijun; Wu, Ning

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收藏 | 浏览/下载：22/0 | 提交时间：2017/09/30

Saccharide Glut1 Drug Design Anticancer Cell Uptake

Temperature dependence of the heterogeneous uptake of acrylic acid on Arizona test dust 期刊论文 OAI收割
JOURNAL OF ENVIRONMENTAL SCIENCES, 2017, 卷号: 53, 页码: 107-112
作者: Liu, Qifan; Wang, Yidan; Wu, Lingyan; Jing, Bo; Tong, Shengrui

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收藏 | 浏览/下载：29/0 | 提交时间：2018/01/15

Heterogeneous Uptake Acrylic Acid Knudsen Cell Uptake Coefficients

Dynamically-enhanced retention of gold nanoclusters in HeLa cells following X-rays exposure: A cell cycle phase-dependent targeting approach 期刊论文 OAI收割
RADIOTHERAPY AND ONCOLOGY, 2016, 卷号: 119, 页码: 544-551
作者: Liu, Yan; Chen, Weiqiang; Zhang, Pengcheng; Jin, Xiaodong; Liu, Xinguo

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收藏 | 浏览/下载：18/0 | 提交时间：2018/05/31

Ionizing radiation Nano-agents Cell cycle Cellular uptake Synergistic chemo-radiotherapy

Dynamically-enhanced retention of gold nanoclusters in hela cells following x-rays exposure: a cell cycle phase-dependent targeting approach 期刊论文 iSwitch采集
Radiotherapy and oncology, 2016, 卷号: 119, 期号: 3, 页码: 544-551
作者: Liu, Yan; Chen, Weiqiang; Zhang, Pengcheng; Jin, Xiaodong; Liu, Xinguo

收藏 | 浏览/下载：29/0 | 提交时间：2019/05/09

Ionizing radiation Nano-agents Cell cycle Cellular uptake Synergistic chemo-radiotherapy

Protein Corona Influences Cellular Uptake of Gold Nanoparticles by Phagocytic and Nonphagocytic Cells in a Size-Dependent Manner 期刊论文 OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2015, 卷号: 7, 期号: 37, 页码: 20568-20575
作者: Cheng, XJ; Tian, X; Wu, AQ; Li, JX; Tian, J

收藏 | 浏览/下载：59/0 | 提交时间：2016/04/18

gold nanoparticle size protein corona cell line uptake level endocytic pathways

Toxicity mechanism of graphene oxide and nitrogen-doped graphene quantum dots in RBCs revealed by surface-enhanced infrared absorption spectroscopy 期刊论文 OAI收割
toxicology research, 2015, 卷号: 4, 期号: 4, 页码: 885-894
作者: Wang,Tiantian; Zhu,Shoujun; Jiang,Xiue

收藏 | 浏览/下载：37/0 | 提交时间：2016/05/20

CELLULAR UPTAKE RED-CELL ADENOSINE-TRIPHOSPHATE MULTIVARIATE-ANALYSIS CARBON NANOPARTICLES GOLD NANOPARTICLES HUMAN ERYTHROCYTES LIPID-MEMBRANES IN-VITRO NANOSHEETS