中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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金属研究所 [39]
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期刊论文 [172]
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Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
Structure-guided design and photochemical synthesis of new carbamo (dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CLpro
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 114, 页码: 9
作者:
Yin, De-Hang
;
Xin, Jie
;
Chen, Shizhao
;
Li, Shuai-Shuai
;
Li, Zi-Ying
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/12/11
SARS-CoV-2
Disulfiram
Carbamo(dithioperoxo)thioates
Photochemistry
3CL pro
Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5
作者:
Shen, Wen
;
Chen, Xinyao
;
Zhou, Liping
;
Cheng, Yan
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/10/21
COVID-19
SARS-CoV-2 3CL pro inhibitor
Drug design
Antiviral activities
Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial
期刊论文
OAI收割
LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13
作者:
Wang, Fuxiang
;
Xiao, Wen
;
Tang, Yimin
;
Cao, Mengli
;
Shu, Dan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
Covid-19
3CL protease inhibitor
SARS-CoV-2 viral load
Alleviation of COVID-19 symptoms
Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12
作者:
Zhu, Mengwei
;
Fu, Tiantian
;
You, Mengyuan
;
Cao, Junyuan
;
Yang, Hanxi
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
COVID-19
SARS-CoV-2
3CL protease
Nirmatrelvir
Peptidomimetic inhibitors
Squeezing More Past Knowledge for Online Class-Incremental Continual Learning
期刊论文
OAI收割
IEEE/CAA Journal of Automatica Sinica, 2023, 卷号: 10, 期号: 3, 页码: 722-736
作者:
Da Yu
;
Mingyi Zhang
;
Mantian Li
;
Fusheng Zha
;
Junge Zhang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/03/02
Catastrophic forgetting
class-incremental learning
continual learning (CL)
experience replay
Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 卷号: 209, 页码: 8
作者:
Zhu, Dafu
;
Su, Haixia
;
Ke, Changqiang
;
Tang, Chunping
;
Witt, Matthias
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15
SARS-CoV-2
3CL protease
Native MS
Traditional Chinese medicine
Natural product
Exploring the migration and transformation of lattice oxygen during chemical looping with NiFe2O(4) oxygen carrier
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2022, 卷号: 429, 页码: 15
作者:
  |  
收藏
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浏览/下载:25/0
  |  
提交时间:2022/09/22
Lattice oxygen
Chemical looping (CL)
NiFe2O4
Migration and transformation
Oxygen carrier (OC)
Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2022, 卷号: 275, 页码: 8
作者:
Zhang, Shihai
;
Pei, Rongjuan
;
Li, Meixia
;
Su, Haixia
;
Sun, Hao
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2021/12/16
COVID-19
SARS-CoV-2
Angiotensin converting enzyme 2 (ACE2)
3CL protease
Ecklonia kurome Okam
Polysaccharide
Clean and effective removal of Cl(-I) from strongly acidic wastewater by PbO2
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL SCIENCES, 2022, 卷号: 120, 页码: 1-8
作者:
Zhao, Jinmin
;
Kong, Linghao
;
Hu, Xingyun
;
Peng, Xianjia
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/02/06
Cl(-I) removal
Strongly acidic wastewater
Cl center dot radicals
center dot OH radicals
PbO2 regeneration