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Benzothiazole amide analogues as antagonists of TRPC 6 channels: A therapeutic approach for kidney fibrosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 16
作者:
Ren, Chunlin
;
Xu, Qiding
;
Luo, Qiusi
;
Qiao, Xue
;
Ding, Taotao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
Transient receptor potential canonical 6
channels
Antagonist
Renal fibrosis
Benzothiazole derivatives
Unilateral ureteral obstruction
Synthesis, photophysical properties and fluorescent application of novel [1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one derivatives
期刊论文
OAI收割
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2025, 卷号: 464, 页码: 11
作者:
Gan, Suya
;
Gao, Li-Xin
;
Cao, Zitong
;
Zhang, Chun
;
Fu, Yiqiu
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2025/04/01
[1
4]triazolo[1
5-a]pyrimidin-7(4H)-one
derivatives
Fluorescence properties
Fe 3+ions
Synthesis and biological evaluation of amino-conjugated bile acid derivatives against non-alcoholic steatohepatitis
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 122, 页码: 6
作者:
Wu, Zhitao
;
Zhang, Mingge
;
Yan, Meng Kun
;
Li, Chenyue
;
Pan, Guoyu
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
Non-alcoholic steatohepatitis (NASH)
Bile acid derivatives
Anti-lipid accumulation activities
Anti-inflammatory activities
Anti-fibrosis activities
Targeting Two Odorant-Binding Proteins in Acyrthosiphon pisum: Discovery of Novel Jasmone Derivatives as Aphid Repellents
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2025, 卷号: 73, 期号: 19, 页码: 11998-12013
作者:
Zhu, Ziwei
;
Li, Huilin
;
Zhu, Wenya
;
Du, Shaoqing
;
Yang, Zhaokai
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
odorant-binding proteins
jasmone derivatives
rational design
aphid repellents
insect behaviorregulators
Synthesis and Evaluation of Optical Properties, SHP2 Inhibitory Activity, and Cellular Imaging for Novel 2-Quinolone Derivatives
期刊论文
OAI收割
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2025, 页码: 10
作者:
Zhang, Chun
;
Yang, Yuting
;
Gao, Li-Xin
;
Gan, Suya
;
Li, Jia
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/05/27
Fluorescent inhibitors
SHP2
2-quinolone derivatives
optical properties
drug tracing
medical diagnosis
Harnessing Functional Food Sources: Deriving Anti-Inflammatory and Antibacterial Naphthalene Derivatives from the Edible Bulbs of
Eleutherine bulbosa
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2025, 卷号: 73, 期号: 7, 页码: 4126-4136
作者:
Gao, Yuan
;
Li, Ying
;
Zhou, Jun-Su
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Eleutherine bulbosa
bioactive components
naphthalene derivatives
anti-inflammatory
antibacterial
Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21
作者:
Sui, Qibang
;
Zhou, Yuanyang
;
Li, Manjia
;
Wang, Dan
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/25
Synthetic lethal
MSI tumors
WRN inhibitors
Triazolo-pyrimidine derivatives
One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18
作者:
Li, Huaxuan
;
Yang, Hong
;
Liu, Li
;
Zheng, Jiahong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/12/11
Protein arginine methyltransferase 5
Nucleoside derivatives
Piperazine
Metabolic stability
Symmetric dimethylarginines
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
Major specialized natural products from the endangered plant
Heptacodium
miconioides,
, potential medicinal uses and insights into its longstanding unresolved systematic classification
期刊论文
OAI收割
PHYTOCHEMISTRY, 2024, 卷号: 228, 页码: 15
作者:
Zhao, Ze-Yu
;
Wan, Jiang
;
Chen, Hao-Wei
;
Sun, Zhong-Shuai
;
Tao, Yu-Tian
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/10/21
Heptacodium miconioides
Caprifoliaceae
Systematic position
Chemotaxonomy
Enantiomeric lignans
Triterpenoids
Quinic acid derivatives
ACL inhibitory