机构

• 上海药物研究所 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2024 [1]
• 2023 [1]
• 2021 [1]
• 2019 [1]
• 2015 [1]
• 2014 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10 作者:  Chen, Guofeng;  Xie, Hang;  Liu, Jiayuan;  Shao, Qiang;  Li, Minjun   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/01/26 Methyl substitution  Selectivity  FABP4 inhibitor  Anti-inflammation  Metabolic stability   Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16 作者:  He, Yulong;  Li, Shunyi;  Zhu, Yueyue;  Wang, Yujie;  Chen, Yuqi   |  收藏  |  浏览/下载：78/0  |  提交时间：2023/10/17 Structure-activity relationship  FABP4 inhibitor  Biphenyl scaffold  Selectivity  Oral bioavailability  Anti-inflammation   Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice 期刊论文  OAI收割 BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 页码: 10 作者:  Chen, Meng-Ting;  Huang, Jun-Shang;  Gao, Ding-Ding;  Li, Ying-Xia;  Wang, He-Yao   |  收藏  |  浏览/下载：30/0  |  提交时间：2021/08/17 combined treatment  FABP4 inhibitor  liver steatosis  obese type 2 diabetes  rosiglitazone   Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16 作者:  He, Yulong;  Dou, Huixia;  Gao, Dingding;  Wang, Ting;  Zhang, Mingming   |  收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01 Dual FABP4/5 inhibitor  Structure-based design  Lipolysis inhibition  Anti-inflammatory effects   Novel fatty acid binding protein 4 (FABP4) inhibitors: Virtual screening, synthesis and crystal structure determination 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 241-250 作者:  Cai, Haiyan;  Liu, Qiufeng;  Gao, Dingding;  Wang, Ting;  Chen, Tiantian   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 FABP4  Inhibitor  Diabetes  Virtual screening  Crystal structure   Small Molecule Inhibitors of Human Adipocyte Fatty Acid Binding Protein (FABP4) 期刊论文  OAI收割 MEDICINAL CHEMISTRY, 2014, 卷号: 10, 期号: 4, 页码: 339-347 作者:  Zhang, Mingming;  Zhu, Weiliang;  Li, Yingxia   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Fatty acid binding protein 4  FABP4  inhibitor  receptor  small molecule  type 2 diabetes   Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 卷号: 20, 期号: 12, 页码: 3675-3679 作者:  Cai, Haiyan;  Yan, Guirui;  Zhang, Xiaodong;  Gorbenko, Olena;  Wang, Heyao   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 FABP4  FABP3  Inhibitor  Selectivity  MD studies  Mutation