中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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机构
上海药物研究所 [11]
西北高原生物研究所 [2]
水生生物研究所 [2]
上海生物化学与细胞生... [1]
合肥物质科学研究院 [1]
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OAI收割 [17]
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期刊论文 [17]
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2022 [1]
2021 [3]
2020 [2]
2018 [2]
2016 [2]
2014 [1]
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学科主题
Cell Biolo... [1]
生物科学 [1]
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浏览/检索结果:
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Modulating effects of RAMPs on signaling profiles of the glucagon receptor family
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 2, 页码: 637-650
作者:
Shao, Lijun
;
Chen, Yan
;
Zhang, Shikai
;
Zhang, Zhihui
;
Cao, Yongbing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
G protein-coupled receptor
Glucagon receptor family
Receptor activity-modulating protein
Signaling
Allosteric modulation
GPCR-RAMP interaction
Receptor pharmacology
Ligand selectivity
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/11/01
cryo-EM structure
G protein-coupled receptor (GPCR)
partial and full agonists
conformational change
desensitization
Structural insights into the activation of human calcium-sensing receptor
期刊论文
OAI收割
ELIFE, 2021, 卷号: 10, 页码: 24
作者:
Chen, Xiaochen
;
Wang, Lu
;
Cui, Qianqian
;
Ding, Zhanyu
;
Han, Li
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
G-protein-coupled receptor
calcium-sensing receptor
cryo-electron microscopy
calcium ions
nanobody
CaSR
GPCR
cryo-EM
None
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:
Chang, Rulue
;
Zhang, Xin
;
Qiao, Anna
;
Dai, Antao
;
Belousoff, Matthew J.
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/12/24
glucagon receptor
glucagon-like peptide-1 receptor
dual agonist
cryo-electron microscopy
single particle analysis
structure-function
structural biology
peptide 15 (P15)
metabolic disorder
G protein?coupled receptor (GPCR)
glucagon
GLP-1 receptor
Pharmacological characterization of mono-, dual- and tri-peptidic agonists at GIP and GLP-1 receptors
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 13
作者:
Yuliantie, Elita
;
Darbalaei, Sanaz
;
Dai, Antao
;
Zhao, Peishen
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
Glucose-dependent insulinotropic peptide receptor
Glucagon-like peptide-1 receptor
Biased agonist
GPCR signaling
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 212-242
作者:
Dal Maso, Emma
;
Zhu, Yue
;
Vi Pham
;
Reynolds, Christopher A.
;
Deganutti, Giuseppe
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
G protein-coupled receptor
Calcitonin receptor
GPCR structure-function
Biased agonism
Molecular modelling
Mutations in the C-terminal region affect subcellular localization of crucian carp herpesvirus (CaHV) GPCR
期刊论文
OAI收割
VIRUS GENES, 2016, 卷号: 52, 期号: 4, 页码: 484-494
作者:
Wang, Jun
;
Gui, Lang
;
Chen, Zong-Yan
;
Zhang, Qi-Ya
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2016/11/21
G protein-coupled receptor (GPCR)
Crucian carp herpesvirus (CaHV)
C-terminal
Subcellular localization
N-myristoylation site
Mutations in the C-terminal region affect subcellular localization of crucian carp herpesvirus (CaHV) GPCR
期刊论文
OAI收割
VIRUS GENES, 2016, 卷号: 52, 期号: 4, 页码: 484-494
作者:
Wang, Jun
;
Gui, Lang
;
Chen, Zong-Yan
;
Zhang, Qi-Ya
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/01/14
G protein-coupled receptor (GPCR)
Crucian carp herpesvirus (CaHV)
C-terminal
Subcellular localization
N-myristoylation site