机构

• 上海药物研究所 [36]
• 昆明植物研究所 [5]
• 地理科学与资源研究所 [2]
• 生物物理研究所 [1]
• 金属研究所 [1]
• 成都生物研究所 [1]
• 更多

采集方式

• OAI收割 [49]

内容类型

• 期刊论文 [41]
• 会议论文 [6]
• 中文期刊论文 [1]
• 学位论文 [1]

发表日期

• 2025 [1]
• 2024 [5]
• 2023 [3]
• 2022 [2]
• 2021 [2]
• 2020 [3]
• 更多

学科主题

• Pharmacolo... [4]
• Chemistry [2]
• Biochemica... [1]
• Biochemist... [1]
• Plant Scie... [1]
• 天然产物研究 [1]
• 更多

筛选

浏览/检索结果: 共49条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Ligand-binding assays validated for quantitative bioanalysis of a novel antibody-drug conjugate in monkey serum and related application in a nonclinical study 期刊论文  OAI收割 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2025, 卷号: 131, 页码: 11 作者:  Hou, Yingying;  Miao, Jie;  Sun, Yajun;  Shi, Lili;  Lu, Ouyang   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/04/01 ADC  LBA  Validation  GLP  PK   Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 5069-5073 作者:  Li, Jie;  Li, Guanyi;  Mai, Yiting;  Liu, Xiao;  Yang, Dehua   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/01/06 GLP-1(9-36)  Cryo-electron microscopy  Metabolite  Allosteric modulation   V1bR enhances glucose-stimulated insulin secretion by paracrine production of glucagon which activates GLP-1 receptor 期刊论文  OAI收割 CELL AND BIOSCIENCE, 2024, 卷号: 14, 期号: 1, 页码: 11 作者:  Yun, Ying;  Guo, Shimeng;  Xie, Xin   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/10/21 Arginine vasopressin  Insulin  Glucagon  V1bR  GLP-1R  Islets  Diabetes   A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19 作者:  Wang, Xiaoyan;  Yun, Ying;  Chen, Lili;  Guo, Shimeng;  Niu, Buying   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/07/12 Diabetes  GLP-1 receptor  Agonist  Structural optimization  Water molecule replacement  Structure activity relationship  Docking simulation   Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in B-arrestin 1/2 signaling 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACOLOGY, 2024, 卷号: 968, 页码: 17 作者:  Lei, Saifei;  Meng, Qian;  Liu, Yanyun;  Liu, Qiaofeng;  Dai, Antao   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/05/22 GLP-1R  B-arrestin 1/2  Biased agonism  Bioluminescence resonance energy transfer  Proteomics profiling   Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database 期刊论文  OAI收割 BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13 作者:  Zhou, Jianxing;  Zheng, You;  Xu, Baohua;  Long, Songjun;  Zhu, Li-e   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/25 GLP-1RAs  Suicidal or self-injurious behaviors  Pharmacovigilance  FAERS database  Type 2 diabetes  Obesity   Four new phenolic compounds from the fruits of Alpinia galanga 期刊论文  OAI收割 PHYTOCHEMISTRY LETTERS, 2023, 卷号: 55, 页码: 75-79 作者:  Liu,Pei;  Wu,Sheng-Li;  Wang,Tian;  Zhang,Xue-Mei;  Geng,Chang-An   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/07/22 Alpinia galanga  Phenolic compounds  PTP1B inhibitory activity  ?-glycosidase inhibitory activity  GLP-1 secretion   Sesquiterpenoids from Alpinia oxyphylla with GLP-1 Stimulative Effects through Ca2+/CaMKII and PKA Pathways and Multiple-Enzyme Inhibition 期刊论文  OAI收割 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 43, 页码: 16148-16159 作者:  Cui,Can;  Wu,Sheng-Li;  Chen,Ji-Jun;  Gongpan,Pianchou   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/07/10 Alpinia oxyphylla  sesquiterpenoids  GLP-1 stimulation  Ca2+/CaMKII and PKA pathways  alpha-glucosidase and PTP1B inhibitory activity   Diarylheptanoids with hypoglycemic potency from the rhizomes of Kaempferia galanga 期刊论文  OAI收割 FITOTERAPIA, 2023, 卷号: 167, 页码: 105502 作者:  Wang,Tian;  Wu,Sheng-Li;  Liu,Pei   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/07/25 Kaempferia galanga  Diarylheptanoids  ?-glucosidase and GPa inhibition  GLP-1 promotion  Antidiabetic effects  INHIBITORS   Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists 期刊论文  OAI收割 PHARMACEUTICALS, 2022, 卷号: 15 作者:  Sun, Lei;  Zheng, Zhi-Ming;  Shao, Chang-Sheng;  Zhang, Zhi-Yong;  Li, Ming-Wei   |  收藏  |  浏览/下载：27/0  |  提交时间：2022/12/22 glucagon-like peptide-1  GLP-1 receptor agonist  functional protein design  molecular dynamics simulation  long-acting antihyperglycemic