机构

• 上海药物研究所 [25]
• 昆明植物研究所 [5]
• 中国科学院大学 [1]
• 海洋研究所 [1]

采集方式

• OAI收割 [31]
• iSwitch采集 [1]

内容类型

• 期刊论文 [32]

发表日期

• 2023 [2]
• 2022 [2]
• 2021 [3]
• 2020 [1]
• 2019 [1]
• 2018 [3]
• 更多

学科主题

• Biochemist... [2]
• Chemistry [2]
• Pharmacolo... [2]

筛选

浏览/检索结果: 共32条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study 期刊论文  OAI收割 JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12 作者:  Zhao, Tian-Tian;  Hu, Hao-Jie;  Gao, Li-Xin;  Zhou, Yu-Bo;  Zhu, Yun-Long   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17 Protein tyrosine phosphatases inhibitors  PTP1B inhibitors  Mechanism study  Molecular dynamics   URSOLIC ACID DERIVATIVES BEARING 1,2,3-TRIAZOLE MOIETIES AS POTENTIAL PTP1B INHIBITORS 期刊论文  OAI收割 CHEMISTRY OF NATURAL COMPOUNDS, 2023, 卷号: 59, 期号: 3, 页码: 508-511 作者:  Liu, Zhe;  Bai, Xueqian;  Sheng, Li;  Sun, Liangpeng;  Li, Jia   |  收藏  |  浏览/下载：44/0  |  提交时间：2023/10/17 ursolic acid  PTP1B inhibitors  dose-dependently  molecular docking   Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文  OAI收割 MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367 作者:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/04/30 (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY   Triterpenoids from Uncaria rhynchophylla and Their PTP1B Inhibitory Activity 期刊论文  OAI收割 PHYTON-INTERNATIONAL JOURNAL OF EXPERIMENTAL BOTANY, 2022, 卷号: 91, 期号: 8, 页码: 1809-1816 作者:  Luo, Shuaibin;  Zhang, Xuemei;  He, Kang;  Zou, Juan;  Geng, Chang-An   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/04/30 Uncaria rhynchophylla  triterpenoids  antidiabetic effects  PTP1B inhibitors  ALKALOIDS   Chemical profiling and antidiabetic potency of Paeonia delavayi: Comparison between different parts and constituents 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 198, 页码: 113998 作者:  Huang,Qian;  Chen,Ji-Jun;  Pan,Yang;  He,Xiao-Feng;  Wang,Yuan   |  收藏  |  浏览/下载：16/0  |  提交时间：2022/04/02 Paeonia delavayi  Chemical comparison  LCMS analyses  Antidiabetic effects  PTP1B/TCPTP selective inhibitors  LIQUID-CHROMATOGRAPHY  MULTIPLE CONSTITUENTS  RAPID IDENTIFICATION  GLYCOSIDES  ROOT  DERIVATIVES  TARGETS  CAPSULE  L.   Diarylheptanoid-chalcone hybrids with PTP1B and alpha-glucosidase dual inhibition from Alpinia katsumadai 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104683 作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Li,Tian-Ze;  Hu,Jing;  Zhang,Xue-Mei   |  收藏  |  浏览/下载：14/0  |  提交时间：2022/04/02 Alpinia katsumadai  Katsumadainols A(1)-A(16)  PTP1B/TCPTP selective inhibitors  alpha-glucosidase inhibitors  Antidiabetic effects  THEORETICAL CALCULATION  ABSOLUTE-CONFIGURATION  SEEDS  BLEPHAROCALYXINS  ADDUCT  MOIETY   The antidiabetic potency of Amomum tsao-ko and its active flavanols, as PTP1B selective and alpha-glucosidase dual inhibitors 期刊论文  OAI收割 INDUSTRIAL CROPS AND PRODUCTS, 2021, 卷号: 160, 页码: 112908 作者:  He,Xiao-Feng;  Chen,Ji-Jun;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xu-Ke   |  收藏  |  浏览/下载：68/0  |  提交时间：2022/04/02 Amomum tsao-ko  Amomutsaokins A-H  Flavanol-menthane conjugates  PTP1B selective inhibitors  alpha-Glucosidase inhibitors  ANTIOXIDANT ACTIVITY  ESSENTIAL OIL  CONSTITUENTS  TANNINS  CREVOST  ACID   Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5 作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya   |  收藏  |  浏览/下载：48/0  |  提交时间：2020/07/01 Heterocyclic bis-aryl amides  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   Identification and characterization of potent and selective inhibitors targeting protein tyrosine phosphatase 1B (PTP1B) 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 16, 页码: 2358-2363 作者:  Jin, Jia;  Ye, Xiaoqing;  Boateng, Derrick;  Dai, Kaili;  Ye, Fei   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/21 PTP1B  TCPTP  Type 2 diabetes  Selective inhibitors  Dihydropyridine thione   Vistriterpenoids A and B, Two New 24-Nor-oleanane Triterpenoids from Dodonaea viscosa 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 11 作者:  Wang, Xiao-Hang;  Zhu, Ke-Xin;  Li, Jing-Ya;  Lei, Chun;  Hou, Ai-Jun   |  收藏  |  浏览/下载：61/0  |  提交时间：2019/01/08 Dodonaea viscosa  vistriterpenoids A and B  triterpenoids  protein tyrosine phosphatase 1b (PTP1B)  PTP1B inhibitors  inhibitory activity