中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [12]
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期刊论文 [55]
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A new paradigm for applying deep learning to protein-ligand interaction prediction
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 3, 页码: 12
作者:
Wang, Zechen
;
Wang, Sheng
;
Li, Yangyang
;
Guo, Jingjing
;
Wei, Yanjie
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/06
protein-ligand interaction
scoring function
deep learning
graph neural network
Wheelchair basketball improves the treatment of urinary tract infection in people with motor disabilities: a clinical trial
期刊论文
OAI收割
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2022, 卷号: 68, 期号: 5, 页码: 559-567
作者:
Cavalcante, Ramirie N.
;
Santos, Adeliana C. S.
;
Rodrigues, Rosilene Andrade Silva
;
Napoleao, Amanda Colichio Bini
;
Balogun, Sikiru O.
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/30
C-reactive protein
Klebsiella pneumoniae
Interleukin-6
Escherichia coli
Sports medicine
Quality of life
RENAL-FUNCTION
EXERCISE
MARKERS
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
  |  
收藏
  |  
浏览/下载:101/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
The new chimeric chiron genes evolved essential roles in zebrafish embryonic development by regulating NAD(+) levels
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2021, 卷号: 64, 期号: 11, 页码: 1929-1948
作者:
Fang,Chengchi
;
Gan,Xiaoni
;
Zhang,Chengjun
;
He,Shunping
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/04/02
new chimeric genes
essential function
NAD plus rate-limiting enzyme
coevolution
COLONY-ENHANCING FACTOR
DE-NOVO ORIGINATION
PHYLOGENETIC ANALYSIS
PROTEIN DIVERSITY
RAPID EVOLUTION
DUPLICATE GENES
GENERATION TIME
PATHWAY
YOUNG
NEOFUNCTIONALIZATION
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:
Chang, Rulue
;
Zhang, Xin
;
Qiao, Anna
;
Dai, Antao
;
Belousoff, Matthew J.
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2020/12/24
glucagon receptor
glucagon-like peptide-1 receptor
dual agonist
cryo-electron microscopy
single particle analysis
structure-function
structural biology
peptide 15 (P15)
metabolic disorder
G protein?coupled receptor (GPCR)
glucagon
GLP-1 receptor
Dietary taurine supplementation to a plant protein source-based diet improved the growth and intestinal immune function of young grass carp (Ctenopharyngodon idella)
期刊论文
OAI收割
AQUACULTURE NUTRITION, 2019, 卷号: 25, 期号: 4, 页码: 873-896
作者:
Yan, Liang-Chao
;
Feng, Lin
;
Jiang, Wei-Dan
;
Wu, Pei
;
Liu, Yang
  |  
收藏
  |  
浏览/下载:178/0
  |  
提交时间:2019/11/29
Ctenopharyngodon idella
diet
fishmeal
intestinal immune function
plant protein source
Taurine
Constructing effective energy functions for protein structure prediction through broadening attraction-basin and reverse Monte Carlo sampling
期刊论文
OAI收割
BMC BIOINFORMATICS, 2019, 卷号: 20, 页码: 10
作者:
Zhang, Haicang
;
Wang, Chao
;
Bu, Dongbo
;
Zheng, Wei-Mou
;
Sun, Shiwei
  |  
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/08/16
Protein structure prediction
Energy function
Attraction-basin
Reverse Monte Carlo sampling
Monte Carlo search
Linear program
Association and Functional Analyses Revealed That PPP1R3B Plays an Important Role in the Regulation of Glycogen Content in the Pacific Oyster Crassostrea gigas
期刊论文
OAI收割
FRONTIERS IN GENETICS, 2019, 卷号: 10, 页码: 16
作者:
Liu, Sheng
;
Li, Li
;
Meng, Jie
;
Song, Kai
;
Huang, Baoyu
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/05/15
oyster
glycogen content
protein phosphatase 1 regulatory subunit 3B (PPP1R3B)
gene function analyses
associated SNPs
Functional and structural profiles of GST gene family from three Populus species reveal the sequence-function decoupling of orthologous genes
期刊论文
OAI收割
NEW PHYTOLOGIST, 2019, 卷号: 221, 期号: 2, 页码: 1060-1073
作者:
Yang, Qi
;
Han, Xue-Min
;
Gu, Jin-Ke
;
Liu, Yan-Jing
;
Yang, Mao-Jun
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/01/06
functional divergence
glutathione S-transferase (GST)
orthologous gene
Populus
protein function
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
;
Feng, Yang
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain