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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [46]
长春应用化学研究所 [6]
昆明植物研究所 [5]
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期刊论文 [71]
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New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Synthesis and Biological Evaluation of β-Lactam Derivatives Targeting Speckle-Type POZ Protein (SPOP)
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 2, 页码: 270-279
作者:
Zhou, Chenmao
;
Hao, Xinyue
;
Chen, Zhengyang
;
Zhang, Runze
;
Zhou, Qian
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/03/13
Speckle-type POZ protein (SPOP)
SPOP inhibitors
Clear cell renal cell carcinoma (ccRCC)
Structure-activityrelationship (SAR)
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
Root-Extracted lignanamides from Limonium gmelinii (Willd.) Kuntze with a potential PTP1B inhibitory activity by regulating PI3K/AKT signaling pathway
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 9
作者:
Tuohongerbieke, Amanguli
;
Liu, Liu
;
Li, Jun
;
Xin, Xuelei
;
Aisa, Haji Akber
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Limonium gmelinii (Willd
) Kuntze
Plumbaginaceae
Lignanamides
Protein tyrosine phosphatase 1B inhibitors
PI3K
AKT Signaling Pathway
NaMLP, a new identified Kunitz trypsin inhibitor regulated synergistically by JA and ethylene, confers Spodoptera litura resistance in Nicotiana attenuata
期刊论文
OAI收割
PLANT CELL REPORTS, 2023
作者:
Yang,Mao
;
Cheng,Junbin
;
Yin,Min
;
Wu,Jinsong
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/05/09
Ethylene
Jasmonate
Miraculin-like protein
Nicotiana
Spodoptera
Trypsin protease inhibitor
BIOINSECTICIDAL ACTIVITY
PHYTOALEXIN SCOPOLETIN
PROTEINASE-INHIBITORS
ALTERNARIA-ALTERNATA
DEFENSE RESPONSES
JASMONATE
MIRACULIN
EXPRESSION
PATHWAYS
PERCEPTION
Artemiprinolides A-M, thirteen undescribed sesquiterpenoid dimers from Artemisia princeps and their antihepatoma activity
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 211, 页码: 113714
作者:
Su,Li-Hua
;
Ma,Wen-Jing
;
Ma,Yun-Bao
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/07/22
Artemisia princeps Pamp
Sesquiterpenoid dimers
Artemiprinolides A-M
Antihepatoma activity
Apoptosis
FARNESYL-PROTEIN TRANSFERASE
ETHANOL EXTRACT
PAMPANINI
INHIBITORS
JACEOSIDIN
Design, synthesis and biological evaluation of novel dihydrobenzodioxine derivatives as HBV capsid protein inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 12
作者:
Liu, Linyue
;
Li, Chuanju
;
Xie, Yong
;
Zhang, Lei
;
Chen, Yunfu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
HBV
Capsid protein inhibitors
Pharmacophore hybrid
Scaffold hopping
HepAD38 cells
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1)
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:
Yu Lijie
;
Feng Bo
;
Wang Zhijia
;
Gao Lixin
;
Zhang Chun
  |  
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2021/11/04
5-phenyl-1,3,4-thiadiazole derivatives
Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)
inhibitors
structure-activity relationships
Design and Synthesis of Alkyl Phenols Inhibitors of Death Associated Apoptotic Protein Kinase 2 (DRAK2)
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3204-3213
作者:
Zheng Zhang
;
Dai Chengqiu
;
Wu Honghong
;
Li Jingya
;
Nan Fajun
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/11/04
death associated apoptotic protein kinase 2
diabetes
alkylphenols
inhibitors