机构

• 化学研究所 [6]
• 上海药物研究所 [2]
• 昆明植物研究所 [1]
• 长春应用化学研究所 [1]

采集方式

• OAI收割 [10]

内容类型

• 期刊论文 [10]

发表日期

• 2021 [1]
• 2018 [1]
• 2015 [1]
• 2014 [1]
• 2013 [1]
• 2012 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共10条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963 作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/04/02 Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN   artificialintelligenceindrugdesign 期刊论文  OAI收割 sciencechinalifesciences, 2018, 卷号: 61, 期号: 10, 页码: 1191 作者:  Zhong Feisheng;  Xing Jing;  Li Xutong;  Liu Xiaohong;  Fu Zunyun   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 PROTEIN-PROTEIN-INTERACTION  MACHINE LEARNING-METHODS  COMPUTATIONAL METHODS  MOLECULAR-PROPERTIES  INTERACTION NETWORKS  NEURAL-NETWORKS  PREDICTION  DOCKING  DISCOVERY  PERMEABILITY  drug design  artificial intelligence  deep learning  QSAR  ADME/T   Force fields and scoring functions for carbohydrate simulation 期刊论文  OAI收割 CARBOHYDRATE RESEARCH, 2015, 卷号: 401, 页码: 73-81 作者:  Xiong, Xiuming;  Chen, Zhaoqiang;  Cossins, Benjamin P.;  Xu, Zhijian;  Shao, Qiang   |  收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Carbohydrate force field  Scoring function  Simulation  Drug design  Carbohydrate-protein interaction   Advantages of proteins being disordered 期刊论文  OAI收割 PROTEIN SCIENCE, 2014, 卷号: 23, 期号: 5, 页码: 539-550 作者:  Liu, Zhirong;  Huang, Yongqi   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/04/09 Intrinsically Disordered Proteins  Protein Function  Flexibility  Protein-protein Interaction  Molecular Recognition  Protein Design  Drug Design   Thermodynamic and kinetic specificities of ligand binding 期刊论文  OAI收割 chemical science, 2013, 卷号: 4, 期号: 6, 页码: 2387-2395 Yan ZQ; Zheng XL; Wang EK; Wang J 收藏  |  浏览/下载：34/0  |  提交时间：2014/04/18 PROTEIN-INTERACTION SPECIFICITY  BIOMOLECULAR INTERFACE BINDING  DRUG DISCOVERY  STATISTICAL-MECHANICS  MOLECULAR RECOGNITION  ENERGY LANDSCAPES  FOLDING FUNNELS  RESIDENCE TIME  DESIGN  DOCKING   Protein-Protein Interaction: Prediction, Design, and Modulation 期刊论文  OAI收割 ACTA PHYSICO-CHIMICA SINICA, 2012, 卷号: 28, 期号: 10, 页码: 2363-2380 作者:  Zhang Chang-Sheng;  Lai Lu-Hua   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/04/09 Protein-protein Interaction  Interaction Prediction  Protein-protein Docking  Protein-protein Interaction Design  Protein Drug  Drug Design   Predicting kinetic constants of protein-protein interactions based on structural properties 期刊论文  OAI收割 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2011, 卷号: 79, 期号: 3, 页码: 720-734 作者:  Bai, Hongjun;  Yang, Kun;  Yu, Daqi;  Zhang, Changsheng;  Chen, Fangjin   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/04/09 Protein Complex Structures  Bayesian Information Criteria  Systems Biology  Protein-protein Interaction Design  Association Rate Constant  Dissociation Rate Constant  Affinity/dissociation Constant  k(On)  k(Off)  k(d)   Intrinsically Disordered Proteins: the New Sequence-Structure-Function Relations 期刊论文  OAI收割 ACTA PHYSICO-CHIMICA SINICA, 2010, 卷号: 26, 期号: 8, 页码: 2061-2072 作者:  Huang Yong-Qi;  Liu Zhi-Rong   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/04/09 Intrinsically Disordered Protein  Protein Folding  Protein Interaction  Molecular Recognition  Protein Structure Prediction  Drug Design   Protein-Protein Interactions: Interface Analysis, Binding Free Energy Calculation and Interaction Design 期刊论文  OAI收割 ACTA PHYSICO-CHIMICA SINICA, 2010, 卷号: 26, 期号: 7, 页码: 1988-1997 作者:  Bai Hong-Jun;  Lai Lu-Hua   |  收藏  |  浏览/下载：18/0  |  提交时间：2019/04/09 Protein-protein Interactions  Basic Property Of Protein-protein Interfaces  Structural Feature Of Protein-protein Interfaces  Binding Free Energy Calculation  Protein-protein Interaction Design  Protein-protein Association/dissociation   Nonnatural protein-protein interaction-pair design by key residues grafting 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 卷号: 104, 期号: 13, 页码: 5330-5335 作者:  Sen Liu;  Liu, Shiyong;  Zhu, Xiaolei;  Liang, Huanhuan;  Cao, Aoneng   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/04/09 De Novo Design Of Protein-protein Interaction Pair  Erythropoietin  Functional Site Grafting  Key Residue At Interface