中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
合肥物质科学研究院 [2]
水生生物研究所 [1]
昆明植物研究所 [1]
过程工程研究所 [1]
海洋研究所 [1]
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采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2024 [4]
2023 [2]
2022 [2]
2021 [1]
2020 [3]
2018 [1]
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学科主题
Oncology; ... [1]
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浏览/检索结果:
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SHP2-Triggered Endothelial Cell Activation Fuels Estradiol-Independent Endometrial Sterile Inflammation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 22
作者:
Pan, Jie
;
Qu, Jiao
;
Fang, Wen
;
Zhao, Lixin
;
Zheng, Wei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/10/21
cell-cell interaction
endometrial hyperplasia
endothelial cell activation
SHP2-RIPK1-AP-1 axis
sterile inflammation
Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 21
作者:
Lan, Yaohan
;
Ji, Yinchun
;
Peng, Xia
;
Duan, Wenhu
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/22
autoimmune disease
necroptosis inhibitor
pharmacokinetic profile
receptor interacting protein kinase 1 (RIPK1)
structural optimization
Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
Qin, Ying
;
Li, Dekang
;
Qi, Chunting
;
Xiang, Huaijiang
;
Meng, Huyan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 747, 页码: 12
作者:
Guo, Shushan
;
Xu, Zhijian
;
Feng, Qilin
;
Zhang, Hui
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/12/11
Autophagy
RRM2
p62
RIPK3
Cholagogue osalmid
Bafilomycin A1
Design, synthesis and biological evaluation of 4-aminoquinoline derivatives as receptor-interacting protein kinase 2 (RIPK2) inhibitors
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2023, 卷号: 38, 期号: 1, 页码: 282-293
作者:
Fan, Tiantian
;
Ji, Yinchun
;
Chen, Danqi
;
Peng, Xia
;
Ai, Jing
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
RIPK2 inhibitor
NOD
immunity
inflammation
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
The pathogenesis of organ fibrosis: Focus on necroptosis
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022
作者:
Hao, Min
;
Han, Xin
;
Yao, Zhouhui
;
Zhang, Han
;
Zhao, Mengting
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2022/12/22
liver fibrosis
lung fibrosis
MLKL
necroptosis
RIPK1
3
tissue fibrosis
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
NLRC3-like 1 inhibits NOD1-RIPK2 pathway via targeting RIPK2
期刊论文
OAI收割
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2020, 卷号: 112, 页码: 12
作者:
Fang, Hong
;
Wu, Xiao Man
;
Hu, Yi Wei
;
Song, Yun Jie
;
Zhang, Jie
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/11/27
Zebrafish
NLRC3-like
Proinflammatory cytokines
NOD1-RIPK2 pathway
Negative regulation