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浏览/检索结果: 共143条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Novel 5-alkenylthiothiazolidinone scaffold discovery as Multi-Chitinases inhibitors to arrest the molting of Asian corn borer 期刊论文  OAI收割 JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1321, 页码: 11 作者:  Shi, Dongmei;  Ji, Xinge;  Zou, Renxuan;  Jiang, Zhiyang;  Duan, Yangwei   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/10/21 5-alkenylthiothiazolidinone scaffold  Multichitinase inhibitor  Amide bond  Asian corn borer  insect growth regulator   The application of nanodiscs in membrane protein drug discovery & development and drug delivery 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2024, 卷号: 12 作者:  Dong, Yingkui;  Tang, Huan;  Dai, Han;  Zhao, Hongxin;  Wang, Junfeng   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/11/20 nanodisc (ND)  membrane protein  drug discovery & development  drug delievery  membrane scaffold protein (MSP)   Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290 作者:  Zheng, Miao;  Feng, Bo;  Zhang, Yumin;  Liu, Xin;  Zhao, Na   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/08/22 Non-covalent PLpro inhibitors  Antiviral activity  Structural-based drug design  Imidazo[4,5-b]pyridine scaffold   Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   In Situ Sodium Chloride Cross-Linked Fish Skin Collagen Scaffolds for Functional Hemostasis Materials 期刊论文  OAI收割 SMALL, 2023, 页码: 13 作者:  Chang, Peng;  Guo, Kai;  Li, Shijie;  Wang, Hongtao;  Tang, Mingqiang   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/01/07 adipose-derived stem cells  exosomes  fish skin scaffold  hemostasis  wound healing   Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9 作者:  Zhou, Qingtong;  Liu, Xiao;  Neri, Dario;  Li, Wenxin;  Favalli, Nicholas   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/12/08 phosphoinositide 3-kinase  drug target  ligand  binding pocket  chemical scaffold   Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16 作者:  He, Yulong;  Li, Shunyi;  Zhu, Yueyue;  Wang, Yujie;  Chen, Yuqi   |  收藏  |  浏览/下载：78/0  |  提交时间：2023/10/17 Structure-activity relationship  FABP4 inhibitor  Biphenyl scaffold  Selectivity  Oral bioavailability  Anti-inflammation   Discovery of pyrido[4,3-d]pyrimidinone derivatives as novel Wee1 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12 作者:  Ye, Qingqing;  Ma, Jingkun;  Wang, Peipei   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/10/17 Wee1 inhibitor  Scaffold hopping   Design, synthesis and biological evaluation of novel dihydrobenzodioxine derivatives as HBV capsid protein inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 12 作者:  Liu, Linyue;  Li, Chuanju;  Xie, Yong;  Zhang, Lei;  Chen, Yunfu   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 HBV  Capsid protein inhibitors  Pharmacophore hybrid  Scaffold hopping  HepAD38 cells   Dynamic process enhancement on chitosan/gelatin/nano-hydroxyapatite-bone derived multilayer scaffold for osteochondral tissue repair 期刊论文  OAI收割 BIOMATERIALS ADVANCES, 2022, 卷号: 133, 页码: 17 作者:  Hu, Xueyan;  Zheng, Shuangshuang;  Zhang, Rui;  Wang, Yiwei;  Jiao, Zeren   |  收藏  |  浏览/下载：28/0  |  提交时间：2023/02/24 Chitosan  gelatin  nano-hydroxyapatite multilayer  scaffold  Bone-derived scaffold  Dynamic environment  Osteochondral tissue regeneration