中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [39]
上海生物化学与细胞生... [6]
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期刊论文 [57]
会议论文 [3]
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Astrocyte atrophy induced by L-PGDS/PGD2/Src signaling dysfunction in the central amygdala mediates postpartum depression
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 359, 页码: 241-252
作者:
Sheng, Zhihao
;
Liu, Qidong
;
Song, Yujie
;
Ye, Binglu
;
Li, Yujie
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/07/12
Prostaglandin D2
Central amygdala
Astrocyte atrophy
Src phosphorylation
Postpartum depression
Structure and function analyses of the SRC gene in Pacific white shrimp
Litopenaeus vannamei
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2024, 卷号: 147, 页码: 12
作者:
Si, Shuqing
;
Zhang, Xiaojun
;
Yu, Yang
;
Zhong, Xiaoyun
;
Zhang, Xiaoxi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/06/04
Litopenaeus vannamei
SRC
Gene structure and function
Gene expression
Growth
Src is a target molecule of mannose against pancreatic cancer cells growth in vitro & amp; in vivo
期刊论文
OAI收割
GLYCOBIOLOGY, 2023, 页码: 18
作者:
Xie, Jianhao
;
Wu, Shengjie
;
Liao, Wenfeng
;
Ning, Jingru
;
Ding, Kan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
computational biology
mannose
network pharmacologypancreatic cancer
Src
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases
期刊论文
OAI收割
CURRENT CANCER DRUG TARGETS, 2023, 卷号: 23, 期号: 10, 页码: 751-763
作者:
Wang, Yiying
;
Wang, Xiaoyu
;
Su, Kexin
;
Yang, Yifu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
c-Src
natural compounds
traditional chinese medicine
cancer
inflammation
osteoblast
Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis
期刊论文
OAI收割
ADVANCED SCIENCE, 2022, 卷号: 9, 期号: 7, 页码: 2103228
作者:
Mao, Jianhua
;
Zhu, Kongkai
;
Long, Zhangbiao
;
Zhang, Huimin
;
Xiao, Bing
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/21
antithrombotic target
bleeding risk
E97A knock-in mice
small molecule
beta 3/Src interaction
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1)
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:
Yu Lijie
;
Feng Bo
;
Wang Zhijia
;
Gao Lixin
;
Zhang Chun
  |  
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2021/11/04
5-phenyl-1,3,4-thiadiazole derivatives
Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)
inhibitors
structure-activity relationships
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
PELP1 Suppression Inhibits Gastric Cancer Through Downregulation of c-Src-PI3K-ERK Pathway
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2020, 卷号: 9, 期号: 1, 页码: 13
作者:
Yan, Hongzhu
;
Sun, Yanling
;
Wu, Qian
;
Wu, Zhe
;
Hu, Meichun
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/04/23
PELP1
oncogene
master gene
gastric cancer
c-Src-PI3K-ERK pathway
chlorpromazine
therapeutic target
The steroid receptor coactivator 1 (SRC1) and 3 (SRC3) recruitment as novel molecular initiating event of 4-n-nonylphenol in estrogen receptor alpha-mediated pathways
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 189, 页码: 1-8
作者:
Ji, Xiaoya
;
Li, Na
;
Yang, Rong
;
Rao, Kaifeng
;
Ma, Mei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/09/15
4-n-Nonylphenol
Estrogenic activity
Molecular initiating event (MIE)
Estrogen receptor alpha (ER alpha)
Steroid receptor coactivator (SRC)
Solution NMR structure and ligand identification of human Gas7 SH3 domain reveal a typical SH3 fold but a non-canonical ligand-binding mode
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 516, 期号: 4, 页码: 1190-1195
作者:
Nie, Yao
;
Zhu, Jiang
;
Ramelot, Theresa A.
;
Kennedy, Michael A.
;
Liu, Maili
  |  
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/10/14
Growth arrest specific 7
Src homology 3
NMR structure
Praline-rich
Phage display