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浏览/检索结果: 共1229条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文  OAI收割 BIOMATERIALS, 2024, 卷号: 305, 页码: 17 作者:  Zhang, Xiaoyu;  Li, Peiwen;  Zhou, Jin;  Zhang, Ziliang;  Wu, Huan   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/04/02 Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK   Activating CD8+ T Cells by Pt(IV) Prodrug-Based Nanomedicine and aPD-L1 Antibody for Enhanced Cancer Immunotherapy 期刊论文  OAI收割 ADVANCED MATERIALS, 2024, 页码: 15 作者:  Wang, Bin;  Zhou, Jingyu;  Li, Ruitong;  Tang, Dongsheng;  Cao, Zheng   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/04/09 chemotherapy  immunotherapy  immunogenic cell death  tumor immune microenvironment   Eliminating drug target interference with specific antibody or its F(ab′)2 fragment in the bridging immunogenicity assay 期刊论文  OAI收割 BIOANALYSIS, 2024, 页码: 14 作者:  Deng, Xiaojie;  Hou, Yingying;  Yuan, Wenyi;  Yang, Hongzhou;  Guo, Ruowen   |  收藏  |  浏览/下载：135/0  |  提交时间：2024/04/09 anti-drug antibody  IgE  immunogenicity  mitigation  target interference   Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity 期刊论文  OAI收割 NATURE IMMUNOLOGY, 2024, 页码: 32 作者:  Long, Xuehui;  Zhang, Sulin;  Wang, Yuliang;  Chen, Jingjing;  Lu, Yanlai   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/25 Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-d]pyrimidin-7(6H)-one" Scaffold for the Treatment of B Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906 作者:  Liang, Xuewu;  Yu, Haolan;  Liang, Renwen;  Feng, Zhuanghui;  Saidahmatov, Abdusaid   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/04/09 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16 作者:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/25 Inhibitor  Cancer  Threonine tyrosine kinase (TTK)  Covalent   Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10 作者:  Chen, Guofeng;  Xie, Hang;  Liu, Jiayuan;  Shao, Qiang;  Li, Minjun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Methyl substitution  Selectivity  FABP4 inhibitor  Anti-inflammation  Metabolic stability   SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10 作者:  Li, Wen-jing;  Xie, Cheng-ying;  Zhu, Xi;  Tang, Jiao;  Wang, Lei   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/19 SIBP-03  HER3  HER3-targeted therapy  neuregulin 1  EGFR  HER2   Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27