机构

• 上海药物研究所 [21]
• 化学研究所 [12]
• 高能物理研究所 [7]
• 长春应用化学研究所 [5]
• 近代物理研究所 [5]
• 金属研究所 [4]
• 更多

采集方式

• OAI收割 [73]
• iSwitch采集 [3]

内容类型

• 期刊论文 [74]
• 会议论文 [2]

发表日期

• 2024 [1]
• 2023 [4]
• 2022 [5]
• 2021 [3]
• 2020 [4]
• 2019 [4]
• 更多

学科主题

• Chemistry [2]
• Chemistry,... [1]
• Science & ... [1]
• 半导体物理 [1]
• 物理化学与绿色催化 [1]

筛选

浏览/检索结果: 共76条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 148, 页码: 15 作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Wu, Jianbo;  Zhang, Ying   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/09/26 Cyclin-dependent kinase 7  Small molecular inhibitor  Triple negative breast cancer  Thieno[3,2-d]pyrimidine derivative   Impact of long-term ultrasound treatment on structural and physicochemical properties of starches differing in granule size 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2023, 卷号: 320, 页码: 14 作者:  Wei, Yiyun;  Li, Guantian;  Zhu, Fan   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/12/13 Starch modification  Starch structure  Physicochemical property  Granular structure  Rheological property  Molecular structure  Quinoa starch  Small granule starch  Corn starch   The in vivo drug delivery pattern of the organelle-targeting small molecules 期刊论文  OAI收割 ADVANCED DRUG DELIVERY REVIEWS, 2023, 卷号: 200, 页码: 14 作者:  Fang, Zhao;  Chen, Hao   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 Organelle-targeting  In vivo imaging  Small molecular probe  Biodistribution  Subcellular structure  Human disease   A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region 期刊论文  OAI收割 JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942 作者:  Jiang, Hao;  Zu, Shijia;  Lu, Yu;  Sun, Zhongya;  Adeerjiang, Akejiang   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/03/27 Small GTPases  Crystal structures of RhoA  Dynamics of switch II  Molecular dynamics simulations  Allosteric pocket   Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文  OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者:  Lai, Mengzhen;  Zhang, Tao;  Chen, Hao;  Song, Peiran;  Tong, Linjiang   |  收藏  |  浏览/下载：122/0  |  提交时间：2023/04/10 fourth-generation EGFR inhibitor  EGFRC797S mutation  NSCLC  drug resistance  small molecular inhibitor   Safety and Efficacy of D-1553 in Patients with KRAS G12C Mutated Non-Small Cell Lung Cancer: A Phase 1 Trial 期刊论文  OAI收割 JOURNAL OF THORACIC ONCOLOGY, 2022, 卷号: 17 作者:  Lu, S.;  Jian, H.;  Zhang, Y.;  Song, Z.;  Zhao, Y.   |  收藏  |  浏览/下载：38/0  |  提交时间：2022/12/23 Non-small cell lung cancer  KRAS G12C mutation  Small molecular inhibitor   Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations 期刊论文  OAI收割 JOURNAL OF MOLECULAR MODELING, 2022, 卷号: 28, 期号: 7, 页码: 184 作者:  Zhang, Qian;  Zhang, Lun;  Jin, Jia;  Fan, Yaohua;  Wang, Xiaoguang   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/21 PRMT5  Small-molecule inhibitors  Virtual screening  Molecular docking  Molecular dynamics simulations   Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11 作者:  Zhao, Zi-tong;  Wang, Jue;  Fang, Lei;  Qian, Xin-di;  Cai, Ying   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/08/16 nanoparticles  molecular targeted therapy  non-small cell lung cancer  dual-responsive  controlled release   Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib 期刊论文  OAI收割 BMC CANCER, 2022, 卷号: 22 作者:  Jin, Ying;  Lin, Chen;  Shi, Xun;  He, Qiong;  Yan, Junrong   |  收藏  |  浏览/下载：87/0  |  提交时间：2022/12/23 Clinical and molecular features  Efficacy and outcome  EGFR T790M mutation  Non-small-cell lung cancer  Osimertinib   Disclosing Potential Key Genes, Therapeutic Targets and Agents for Non-Small Cell Lung Cancer: Evidence from Integrative Bioinformatics Analysis 期刊论文  OAI收割 VACCINES, 2022, 卷号: 10, 期号: 5, 页码: 20 作者:  Mosharaf, Md Parvez;  Reza, Md Selim;  Gov, Esra;  Mahumud, Rashidul Alam;  Mollah, Md Nurul Haque   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/12/07 non-small cell lung cancer  gene expression profiles  molecular signatures  therapeutic targets and agents  integrated bioinformatics approaches