机构

• 上海药物研究所 [8]
• 大连化学物理研究所 [2]
• 化学研究所 [1]
• 昆明植物研究所 [1]
• 中国科学院大学 [1]
• 长春应用化学研究所 [1]
• 更多

采集方式

• OAI收割 [14]
• iSwitch采集 [1]

内容类型

• 期刊论文 [15]

发表日期

• 2024 [1]
• 2021 [1]
• 2019 [1]
• 2016 [3]
• 2012 [3]
• 2011 [1]
• 更多

学科主题

• Chemistry [1]
• Medicinal [1]
• Organic [1]

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Identification and biological evaluation of fused tetrahydroisoquinoline derivatives as Wnt/β-catenin signaling inhibitors to suppress colorectal cancer 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 276, 页码: 16 作者:  Zhou, Jianhui;  Xu, Beibei;  Shen, Qianwen;  Zhang, Zhenwei;  Hu, Yuting   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/09/26 Key & Oslash  Colorectal cancer  Wnt/ beta-catenin  Hsp90  Tetrahydroisoquinoline  rds   Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20 作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia   |  收藏  |  浏览/下载：45/0  |  提交时间：2021/05/24 PDE4 inhibitors  Tetrahydroisoquinoline  Antipsoriasis   Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333 作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 PRMT5 inhibitors  N-Substituted 1,2,3,4-tetrahydroisoquinoline derivatives  Anti-tumor   Design, synthesis and biological evaluation of novel tetrahydroisoquinoline quaternary derivatives as peripheral kappa-opioid receptor agonists 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 13, 页码: 2964-2970 作者:  Guo, Ting;  Gan, Zongjie;  Chen, Jie;  Wang, Dechuan;  He, Ling   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Tetrahydroisoquinoline quaternary derivatives  Peripheral  kappa-Opioid receptor agonists   Solvent-promoted highly selective dehydrogenation of tetrahydroisoquinolines without catalyst and hydrogen acceptor 期刊论文  OAI收割 TETRAHEDRON LETTERS, 2016, 卷号: 57, 期号: 7, 页码: 747-749 作者:  Feng, Guang-Shou;  Ji, Yue;  Liu, Hui -Fang;  Shi, Lei;  Zhou, Yong-Gui   |  收藏  |  浏览/下载：10/0  |  提交时间：2019/06/20 Tetrahydroisoquinoline  Partial Dehydrogenation  Imine   Tetrahydroisoquinolines as novel histone deacetylase inhibitors for treatment of cancer 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 93-99 作者:  Chen, Danqi;  Shen, Aijun;  Fang, Guanghua;  Liu, Hongchun;  Zhang, Minmin   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Histone deacetylases inhibitor  Anticancer  Tetrahydroisoquinoline  Structure-activity relationship   Flexible Synthesis of Enantiomeric and Racemic 3-Hydroxymethyl-1,2,3,4-tetrahydroisoquinolines via Bischler-Napieralski Reaction 期刊论文  OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2012, 卷号: 28, 期号: 5, 页码: 843-846 作者:  Kang Chuan-qing;  Du Zhi-jun;  Wang Lan-lan;  Chen Yu;  Qiu Xue-peng   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/04/09 Bischler-napieralski Reaction  Racemerization  1  2  3  4-tetrahydroisoquinoline   Flexible Synthesis of Enantiomeric and Racemic 3-Hydroxymethyl-1,2,3,4-tetrahydroisoquinolines via Bischler-Napieralski Reaction 期刊论文  OAI收割 chemical research in chinese universities, 2012, 卷号: 28, 期号: 5, 页码: 843-846 Kang CQ; Du ZJ; Wang LL; Chen Y; Qiu XP; Guo HQ; Gao LX 收藏  |  浏览/下载：28/0  |  提交时间：2013/10/09 PHENYLETHANOLAMINE N-METHYLTRANSFERASE  PICTET-SPENGLER REACTION  BINDING-SITE  TETRAHYDROISOQUINOLINE  DERIVATIVES  INHIBITORS   Enantioselective Iridium-Catalyzed Hydrogenation of 3,4-Disubstituted Isoquinolines 期刊论文  OAI收割 angewandte chemie-international edition, 2012, 卷号: 51, 期号: 33, 页码: 8286-8289 作者:  Shi, Lei;  Ye, Zhi-Shi;  Cao, Liang-Liang;  Guo, Ran-Ning;  Hu, Yue 收藏  |  浏览/下载：17/0  |  提交时间：2015/11/09 asymmetric catalysis  hydrogenation  iridium  isoquinoline  1  2  3  4-tetrahydroisoquinoline   FeCl3 center dot 6H(2)O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines: substrate extension and product utilization 期刊论文  OAI收割 TETRAHEDRON, 2011, 卷号: 67, 期号: 5, 页码: 842-848 作者:  Zhang, Jing;  Wu, Kui;  Wang, Meining;  Jiang, Jianqin;  Zhang, Ao   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 1-Substituted benzazepine  Tetrahydroisoquinoline  Ring arrangement  Iron (III) chloride  Tetrahydropyrimidin-4(1H)-one