机构

• 上海药物研究所 [17]
• 金属研究所 [7]
• 水生生物研究所 [6]
• 过程工程研究所 [6]
• 上海生物化学与细胞生... [6]
• 沈阳自动化研究所 [6]
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采集方式

• OAI收割 [81]
• iSwitch采集 [8]

内容类型

• 期刊论文 [84]
• 会议论文 [5]

发表日期

• 2024 [3]
• 2023 [3]
• 2022 [3]
• 2020 [3]
• 2019 [2]
• 2018 [12]
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学科主题

• Chemistry [3]
• Materials ... [2]
• Physics [2]
• Biochemica... [1]
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筛选

浏览/检索结果: 共89条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 AI-driven antibody design with generative diffusion models: current insights and future directions 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10 作者:  He, Xin-heng;  Li, Jun-rui;  Xu, James;  Shan, Hong;  Shen, Shi-yi   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/11/05 antibodies  generative model  diffusion  de novo antibody design  CDR optimization  model evaluation   Functional Divergence in the Affinity and Stability of Non-Canonical Cysteines and Non-Canonical Disulfide Bonds: Insights from a VHH and VNAR Study 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 18, 页码: 16 作者:  Xu, Mingce;  Zhao, Zheng;  Deng, Penghui;  Sun, Mengsi;  Chiu, Cookson K. C.   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/12/20 single-domain antibodies  disulfide bonds  cysteines  nanobodies  intrabodies   创新生物技术药物研发进展 期刊论文  OAI收割 生命科学, 2024, 卷号: 36, 期号: 11, 页码: 1321 作者:  黄瑶庆;  李子艳;  王春丽;  刘丽丽   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/02/28 antibody drug conjugates  bispecific antibodies  mRNA  CRISPR/Cas9  抗体药物偶联物  双特异性抗体  mRNA  CRISPR/Cas9   Multi-omics for COVID-19: driving development of therapeutics and vaccines 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 9, 页码: 30 作者:  Guo, Mengyu;  Xiong, Muya;  Peng, Jinying;  Guan, Tong;  Su, Haixia   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/12/19 COVID-19  SARS-CoV-2  multi-omics  antibodies  small-molecule drugs  vaccines   Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9 作者:  Li, Hua-ying;  Chen, Yi-li;  Deng, Xiang-nan;  Li, Huan-huan;  Tan, Jie   |  收藏  |  浏览/下载：42/0  |  提交时间：2023/10/17 cancer immunotherapy  B7-H3  PD-L1  bispecific antibodies  VHH  antibody-dependent cell-mediated cytotoxicity (ADCC)   Prevalence and influencing factors of suicide in first-episode and drug-naive young major depressive disorder patients with impaired fasting glucose: a cross-sectional study 期刊论文  OAI收割 FRONTIERS IN PSYCHIATRY, 2023, 卷号: 14, 页码: 10 作者:  Li, Yifan;  Liao, Zhenjiang;  Huang, Qiuping;  Wang, Qianjin;  Ren, Honghong   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/09 anxiety  depression disorder  suicide attempts  impaired fasting glucose  thyroid antibodies  blood lipids   Development of a variant of dinutuximab with enhanced antitumor efficacy and reduced induction of neuropathic pain 期刊论文  OAI收割 FEBS OPEN BIO, 2022, 卷号: 12, 期号: 9, 页码: 1644-1656 作者:  Liu, Xin-Yuan;  Chen, Yi-Li;  Liu, Guo-Jian;  Deng, Xiang-Nan;  Cui, Yue   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/09/30 ADCC  affinity maturation  antibody engineering  anti-GD2 antibodies  engineered Fc domain  humanized   Targeted Delivery of Chemotherapeutic Agents for Osteosarcoma Treatment 期刊论文  OAI收割 FRONTIERS IN ONCOLOGY, 2022, 卷号: 12, 页码: 14 作者:  Xie, Duoli;  Wang, Zhuqian;  Li, Jie;  Guo, De-an;  Lu, Aiping   |  收藏  |  浏览/下载：19/0  |  提交时间：2022/06/15 osteosarcoma  targeted delivery  chemotherapeutic agents  ligand-based delivery systems  antibodies   Total synthesis of Lentinus giganteus glycans with antitumor activities via stereoselective alpha-glycosylation and orthogonal one-pot glycosylation strategies 期刊论文  OAI收割 CHEMICAL SCIENCE, 2022, 卷号: 13, 期号: 26, 页码: 7755-7764 作者:  Zhang, Yunqin;  Hu, Yanlei;  Liu, Shanshan;  He, Haiqing;  Sun, Roujing   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/04/30 1,2-CIS O-GLYCOSYLATION  SELECTIVE SYNTHESIS  CHEMICAL-SYNTHESIS  OLIGOSACCHARIDE  GALACTOSYLATION  POLYSACCHARIDE  ALKYNYLBENZOATES  CONJUGATION  ANTIBODIES  CATALYSIS   Bio-mimic particles for the enhanced vaccinations: Lessons learnt from the natural traits and pathogenic invasion 期刊论文  OAI收割 Advanced Drug Delivery Reviews, 2021, 卷号: 176 作者:  Wu, Sihua;  Xia, Yufei;  Hu, Yuning;  Ma, Guanghui   |  收藏  |  浏览/下载：0/0  |  提交时间：2023/06/21 Biomimetics - Antibodies - Immune system - T-cells - Pathogens - Antigens