机构

• 上海药物研究所 [25]
• 长春应用化学研究所 [13]
• 化学研究所 [3]
• 过程工程研究所 [3]
• 烟台海岸带研究所 [3]
• 金属研究所 [1]
• 更多

采集方式

• OAI收割 [54]

内容类型

• 期刊论文 [54]

发表日期

• 2024 [1]
• 2023 [1]
• 2022 [2]
• 2021 [3]
• 2020 [1]
• 2019 [2]
• 更多

学科主题

• Chemistry [3]
• Biochemist... [1]
• Biology [1]
• Engineerin... [1]
• Materials ... [1]
• Pharmacolo... [1]
• 更多

筛选

浏览/检索结果: 共54条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Preparation of Doxorubicin-Loaded Carboxymethyl-beta-Cyclodextrin/Chitosan Nanoparticles with Antioxidant, Antitumor Activities and pH-Sensitive Release 期刊论文  OAI收割 MARINE DRUGS, 2022, 卷号: 20, 期号: 5, 页码: 18 作者:  Mi, Yingqi;  Zhang, Jingjing;  Tan, Wenqiang;  Miao, Qin;  Li, Qing   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/07/26 chitosan nanoparticles  cyclodextrin  antioxidant activity  antitumor activity  drug release   Preparation of Doxorubicin-Loaded Carboxymethyl-beta-Cyclodextrin/Chitosan Nanoparticles with Antioxidant, Antitumor Activities and pH-Sensitive Release 期刊论文  OAI收割 MARINE DRUGS, 2022, 卷号: 20, 期号: 5, 页码: 18 作者:  Mi, Yingqi;  Zhang, Jingjing;  Tan, Wenqiang;  Miao, Qin;  Li, Qing   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/11/15 chitosan nanoparticles  cyclodextrin  antioxidant activity  antitumor activity  drug release   New synthetic adriamycin-incorporated chitosan nanoparticles with enhanced antioxidant, antitumor activities and pH-sensitive drug release 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 11 作者:  Mi, Yingqi;  Chen, Yuan;  Gu, Guodong;  Miao, Qin;  Tan, Wenqiang   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/06/16 Chitosan  Drug release  Cell viability  Antitumor activity   Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng   |  收藏  |  浏览/下载：73/0  |  提交时间：2021/11/04 multiple myeloma  HDAC inhibitor  bisthianostat  pharmacodynamics  pharmacokinetics  phase 1a clinical trial  antitumor drug   Chitosan oligosaccharide modified liposomes enhance lung cancer delivery of paclitaxel 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Miao, Yun-qiu;  Chen, Ming-shu;  Zhou, Xin;  Guo, Lin-miao;  Zhu, Jing-jing   |  收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24 lung cancer  antitumor  chitosan oligosaccharide  liposomes  paclitaxel  drug delivery  nanomedicine   Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14 作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao   |  收藏  |  浏览/下载：54/0  |  提交时间：2020/07/01 lnterleukin-1 receptor associated kinase 4  Imidazol1,2-6]pyridazine  Diffuse large B-cell lymphoma  Drug design  Antitumor agents   The immunostimulatory effects and pro-apoptotic activity of rhCNB against Lewis lung cancer is mediated by Toll-like receptor 4 期刊论文  OAI收割 CANCER MEDICINE, 2019, 卷号: 8, 期号: 9, 页码: 4441-4453 作者:  Yang, Jinju;  Zhang, Hongwei;  Zhu, Ziwei;  Gao, Yadan;  Xiang, Benqiong   |  收藏  |  浏览/下载：74/0  |  提交时间：2019/10/18 antitumor drug  antitumor immunity  innate immunity  rhCNB  Toll-like receptor 4   trailbasedgenedeliveryandtherapeuticstrategies 期刊论文  OAI收割 actapharmacologicasinica, 2019, 卷号: 40, 期号: 11, 页码: 1373 作者:  Zhong Huihai;  Wang Huiyuan;  Li Jian;  Huang Yongzhuo   |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 APOPTOSIS-INDUCING LIGAND  MESENCHYMAL STEM-CELLS  PROSTATE-CANCER CELLS  DEATH RECEPTOR 5  CO-DELIVERY  IN-VIVO  MEDIATED APOPTOSIS  ANTITUMOR-ACTIVITY  TUMORICIDAL ACTIVITY  PROTEIN EXPRESSION  TRAIL  gene delivery  gene therapy  DNA  drug delivery systems  non-viral vectors  cancer therapy