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浏览/检索结果: 共22条，第1-10条 帮助

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Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:  Chen, Xuetao;  Wu, Tingting;  Du, Zhiyan;  Kang, Wenjing;  Xu, Rujun
  |  收藏  |  浏览/下载：40/0  |  提交时间：2024/02/27
Structure-based identification of new orally bioavailable BRD9-PROTACs for treating acute myelocytic leukemia 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 262, 页码: 18
作者:  Zhang, Jingyu;  Duan, Haiting;  Gui, Renzhao;  Wu, Mingfei;  Shen, Liteng
  |  收藏  |  浏览/下载：138/0  |  提交时间：2023/12/19
Discovery of new small molecule inhibitors of the BPTF bromodomain 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453
作者:  Liang, Xiaochen;  Cao, Yu;  Duan, Zhe;  Wang, Mingchen
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/27
Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16
作者:  Chen, Zonglong;  Li, Jiayi;  Yang, Hong;  He, Yulong;  Shi, Qiongyu
  |  收藏  |  浏览/下载：53/0  |  提交时间：2022/08/16
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15
作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu
  |  收藏  |  浏览/下载：55/0  |  提交时间：2022/08/16
Discovery of CECR2 Bromodomain Inhibitors with High Selectivities over BPTF Bromodomain 期刊论文  OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 2072-2080
作者:  Lu, Haibo;  Zu, Shijia;  Duan, Zhe;  Feng, Yueyao;  Wang, Jie
  |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16

Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold

 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 123, 页码: 12
作者:  Lu, Haibo;  Lu, Tian;  Zu, Shijia;  Duan, Zhe;  Guang, Yiman
  |  收藏  |  浏览/下载：38/0  |  提交时间：2022/08/16
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
  |  收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan
  |  收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:  Zhang, Feng-cai;  Sun, Zhong-ya;  Liao, Li-ping;  Zuo, Yu;  Zhang, Dan
  |  收藏  |  浏览/下载：63/0  |  提交时间：2020/07/01