中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [63]
金属研究所 [11]
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期刊论文 [137]
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浏览/检索结果:
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Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12, 页码: 20
作者:
Wang, Hua
;
Tang, Shijie
;
Wu, Qibiao
;
He, Yayi
;
Zhu, Weikang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/02/28
EGFR-mutant lung cancer
adeno-to-squamous transition
tyrosine kinase inhibitor resistance
transcription factor network
RAPGEF3
Confined copper depletion via a hydrogel platform for reversing dabrafenib/cetuximab resistance in BRAFV600E-mutant V600E-mutant colorectal cancer
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 375, 页码: 11
作者:
Wang, Jue
;
Sun, Xiangshi
;
Zhao, Zhiwen
;
Wang, Guanru
;
Wang, Dangge
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/11/05
Colorectal cancer
Copper depletion
Drug resistance
Hydrogel
Nanoparticles
Targeting EGFR with molecular degraders as a promising strategy to overcome resistance to EGFR inhibitors
期刊论文
OAI收割
FUTURE MEDICINAL CHEMISTRY, 2024, 页码: 22
作者:
Wang, Qiangfeng
;
Zhu, Yumeng
;
Pei, Junping
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/10/21
cancer
degrader
EGFR
lysosome-based degradation
PROTAC
resistance
Imaging of carboxylesterase 2 expression changes in colitis and colon cancer chemotherapy via a fluorescent probe
期刊论文
OAI收割
SENSORS AND ACTUATORS B-CHEMICAL, 2024, 卷号: 409, 页码: 9
作者:
Wang, Lingxiao
;
Wang, Lingyun
;
Sun, Xiao
;
Fu, Lili
;
Sun, Mingzhao
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/10/24
Carboxylesterase 2
Fluorescent probe
Colitis
Colon cancer
Chemotherapy resistance
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Smart drug delivery systems to overcome drug resistance in cancer immunotherapy
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2023, 卷号: 20, 期号: 4, 页码: 248-267
作者:
Yi, Wenzhe
;
Yan, Dan
;
Wang, Dangge
;
Li, Yaping
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
Cancer immunotherapy
drug resistance
smart drug delivery system
immunosuppressive microenvironment
immune cell
Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Anti-tumor Activity of Disulfiram and Cisplatin in Ovarian Cancer
期刊论文
OAI收割
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23
作者:
Du, Ruiping
;
Sun, Feilong
;
Li, Kai
;
Qi, Jian
;
Zhong, Wen
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/11/10
Disulfiram
cisplatin resistance
ovarian cancer
proteomics analysis
SMAD3
lactate dehydrogenase
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
作者:
Guo,Xiuping
;
Li,Rui
;
Cui,Jinjin
;
Hu,Chujuan
;
Yu,Haoyang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/09
Erigeron breviscapus injection
Dengzhanxixin
Erigeron breviscapus (Vant
) Hand
-Mazz
colorectal cancer
necroptosis
drug resistance
TUMOR-NECROSIS-FACTOR
COLORECTAL-CANCER
NATURAL COMPOUNDS
SCUTELLARIN
APOPTOSIS
PROLIFERATION
MACROPHAGES
MIGRATION
INVASION
THERAPY
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies