机构

• 上海药物研究所 [12]
• 金属研究所 [4]
• 化学研究所 [4]
• 沈阳应用生态研究所 [2]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [23]

发表日期

• 2023 [3]
• 2018 [1]
• 2017 [2]
• 2015 [1]
• 2014 [4]
• 2013 [2]
• 更多

学科主题

• Crystallog... [1]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Design, synthesis, and STING-agonistic activity of benzo[b]thiophene-2-carboxamide derivatives 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2023, 页码: 10 作者:  Zhou, Rongyao;  Wang, Xiyuan;  Zhang, Deqiang;  Zhan, Zhengsheng;  Duan, Wenhu   |  收藏  |  浏览/下载：12/0  |  提交时间：2023/12/08 STING  CDN  Benzo[b]thiophene-2-carboxamide  Cellular activity   Optimization of carbazole carboxamide RORγt agonists: Challenges in improving the metabolic stability and maintaining the agonistic activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 251, 页码: 115213 作者:  Sun, Nannan;  Yu, Mingcheng;  Jiang, Zhengyuan;  Yang, Feng;  Lu, Lixue   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/27 ROR?t agonists  Carbazole carboxamide  Agonistic activity  Metabolic stability  Co-crystallization  Molecular docking   Molecular Modeling Studies on Carbazole Carboxamide Based BTK Inhibitors Using Docking and Structure-Based 3D-QSAR 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 4 作者:  Li, Rui;  Du, Yongli;  Gao, Zhipei;  Shen, Jingkang   |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 rheumatoid arthritis (RA)  Broton's tyrosine kinase (BTK)  carbazole carboxamide derivatives  3D-QSAR  comparative molecular field analysis (CoMFA)  comparative molecular similarity indices analysis (CoMSIA)   Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents 期刊论文  OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372 作者:  Zhang Lan;  Deng Xinshan;  Wu Jiaofeng;  Meng Guangpeng;  Liu Congchong   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/02/02 MOLECULAR TARGETED DRUGS  TYROSINE KINASE  CANCER-CELLS  EGFR  RESISTANCE  POTENT  DISCOVERY  NSCLC  Anticancer activity  Epidemal growth factor receptor(EGFR) inhibitor  N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative   Design, Synthesis and Biological Activities of N-(Furan-2-ylmethyl)-1H-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents 期刊论文  OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017, 卷号: 33, 期号: 3, 页码: 365-372 作者:  Zhang Lan;  Deng Xinshan;  Wu Jiaofeng;  Meng Guangpeng;  Liu Congchong   |  收藏  |  浏览/下载：59/0  |  提交时间：2021/02/02 MOLECULAR TARGETED DRUGS  TYROSINE KINASE  CANCER-CELLS  EGFR  RESISTANCE  POTENT  DISCOVERY  NSCLC  Anticancer activity  Epidemal growth factor receptor(EGFR) inhibitor  N-( Furan-2-ylmethyl)-1H-indole3-carboxamide derivative   Discovery of potent 1H-imidazo[4,5-b]pyridine-based c-Met kinase inhibitors via mechanism-directed structural optimization 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 3, 页码: 708-716 作者:  An, Xiao-De;  Liu, Hongyan;  Xu, Zhong-Liang;  Jin, Yi;  Peng, Xia   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 c-Met tyrosine kinase  Small molecule inhibitor  Imidazonaphthyridinone  Imidazopyridine  Binding mode  Pyridone-3-carboxamide  Cyclopropane-1,1-dicarboxamide   Discovering novel anti-HCV compounds with inhibitory activities toward HCV NS3/4A protease 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 8, 页码: 1074-1081 作者:  Yu, Ye;  Jing, Jing-feng;  Tong, Xian-kun;  He, Pei-lan;  Li, Yuan-chao   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 hepatitis C virus  NS3/4A protease  secreted embryonic alkaline phosphatase (Seap)  2,4-diaminoquinazoline  carboxamide  telaprevir   Design, synthesis, and biological evaluation of novel piperidine-4-carboxamide derivatives as potent CCR5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 71, 页码: 259-266 作者:  Hu, Suwen;  Gu, Quan;  Wang, Zhilong;  Weng, Zhiyong;  Cai, Yunrui   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 CCR5 inhibitor  Anti-HIV-1 agent  Piperidine-4-carboxamide derivatives   A three-component one-pot synthesis of 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2014, 卷号: 25, 期号: 3, 页码: 411-414 作者:  Zhao HaiLong;  Zhou Jie;  Song HongRui;  Xu BaiLing   |  收藏  |  浏览/下载：151/0  |  提交时间：2021/02/02 HUMAN PIN1 INHIBITORS  BIOLOGICAL EVALUATION  DERIVATIVES  AGENTS  4-Aminothiazole-5-carboxamide  Potassium methyl cyanimidodithiocarbonate  Acetamide