中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
化学研究所 [1]
沈阳自动化研究所 [1]
合肥物质科学研究院 [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2021 [1]
2017 [3]
2015 [1]
2014 [1]
2013 [2]
2012 [1]
更多
学科主题
应用光学技术 [1]
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浏览/检索结果:
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Discovery of New alpha-Glucosidase Inhibitors: Structure-Based Virtual Screening and Biological Evaluation
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 9
作者:
Liu, Shan-Kui
;
Hao, Haifang
;
Bian, Yuan
;
Ge, Yong-Xi
;
Lu, Shengyuan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
α
-glycosidase
virtual screening
cytotoxicity
type 2 diabetes
molecular docking
W2476 ameliorates beta-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1024-1037
作者:
Li, Ting
;
Lin, Guang-yao
;
Zhong, Li
;
Zhou, Yan
;
Wang, Jia
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
diabetes
glucose
TXNIP
beta-cells
W2476
high-throughput screening
w2476amelioratescelldysfunctionandexertstherapeuticeffectsinmousemodelsofdiabetesviamodulationofthethioredoxininteractingproteinsignalingpathway
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 7, 页码: 1022
作者:
Ll Ting
;
Lin Guangyao
;
Zhong Li
;
Zhou Yan
;
Wang Jia
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
diabetes
glucose
TXNIP
p-cells
W2476
high-throughput screening
W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway
期刊论文
OAI收割
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1022
作者:
Ll Ting
;
Lin Guangyao
;
Zhong Li
;
Zhou Yan
;
Wang Jia
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
diabetes
glucose
TXNIP
p-cells
W2476
high-throughput screening
Novel fatty acid binding protein 4 (FABP4) inhibitors: Virtual screening, synthesis and crystal structure determination
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 241-250
作者:
Cai, Haiyan
;
Liu, Qiufeng
;
Gao, Dingding
;
Wang, Ting
;
Chen, Tiantian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
FABP4
Inhibitor
Diabetes
Virtual screening
Crystal structure
Discovery and characterization of novel small-molecule agonists of G protein-coupled receptor 119
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 4, 页码: 540-548
作者:
Zhang, Shu-yong
;
Li, Jing
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
GPCR
GPR119
PSN632408
AR231453
high-throughput screening
cAMP
Ca2+
beta-cell
insulin
obesity
type 2 diabetes mellitus
Development of microfluidic-based telemedicine for diabetes care and screening
期刊论文
OAI收割
TRANSACTIONS OF THE INSTITUTE OF MEASUREMENT AND CONTROL, 2013, 卷号: 35, 期号: 7, 页码: 893-900
作者:
Yao P(姚萍)
;
Tong ZH(童兆宏)
;
Zhan ZK(詹志坤)
;
Hua JN(化建宁)
;
Dong ZL(董再励)
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2013/12/27
Chemiluminescence immunoassay
diabetes screening
insulin detection
microfluidic system
telemedicine
Classification of Skin Autofluorescence Spectrum using Support Vector Machine in Type 2 Diabetes Screening
期刊论文
OAI收割
journal of innovative optical health sciences, 2013
作者:
Yikun Wang
;
Ling Zhu
;
Long Zhang
;
Yuanzhi Zhang
;
Yong Liu
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2014/12/14
Skin autofluorescence
support vector machines algorithm
type 2 diabetes
noninvasive screening
Identification of diverse dipeptidyl peptidase IV inhibitors via structure-based virtual screening
期刊论文
OAI收割
JOURNAL OF MOLECULAR MODELING, 2012, 卷号: 18, 期号: 9, 页码: 4033-4042
作者:
Li, Cui
;
Lu, Weiqiang
;
Lu, Chunhua
;
Xiao, Wen
;
Shen, Xu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Dipeptidyl peptidase IV
Molecular docking
Pharmacophore modeling
Type II diabetes
Virtual screening
Drug-target network and polypharmacology studies of a Traditional Chinese Medicine for type II diabetes mellitus
期刊论文
OAI收割
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2011, 卷号: 35, 期号: 5, 页码: 293-297
作者:
Gu, Jiangyong
;
Zhang, Hu
;
Chen, Lirong
;
Xu, Shun
;
Yuan, Gu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/04/09
Type Ii Diabetes
Network Analysis
Virtual Screening
Traditional Chinese Medicine
Drug-target Network
Polypharmacology