机构

• 上海药物研究所 [14]
• 上海生物化学与细胞生... [1]
• 沈阳自动化研究所 [1]
• 生态环境研究中心 [1]

采集方式

• OAI收割 [17]

内容类型

• 期刊论文 [17]

发表日期

• 2025 [1]
• 2024 [1]
• 2022 [1]
• 2020 [1]
• 2018 [1]
• 2016 [4]
• 更多

学科主题

• Biochemist... [1]

筛选

浏览/检索结果: 共17条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery and optimization of novel indolecarboxylic acid derivative as potent glucagon-like peptide-1 receptor agonists 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2025, 页码: 23 作者:  Zhao, Wanting;  Yin, Yuqian;  Shi, Zhuo;  Yang, Ke;  Li, Xinglin   |  收藏  |   An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG 期刊论文  OAI收割 BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14 作者:  Liu, Zhipei;  Wang, Feng;  Yuan, Hui;  Tian, Fuyun;  Yang, Chuanyan   |  收藏  |   Molecular Determinants for the High-Affinity Blockade of Human Ether-a-go-go-Related Gene K+ Channel by Tolterodine 期刊论文  OAI收割 JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022, 卷号: 80, 期号: 5, 页码: 679-689 作者:  Wang, Na;  Yang, Yang;  Wen, Jing;  Fan, Xin-Rong;  Li, Jian   |  收藏  |   Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2020, 卷号: 103, 页码: 10 作者:  Song, Runzhe;  Wang, Yue;  Wang, Minghui;  Gao, Ruixuan;  Yang, Teng   |  收藏  |   Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections 期刊论文  OAI收割 ACS INFECTIOUS DISEASES, 2018, 卷号: 4, 期号: 3, 页码: 208-217 作者:  Li, Baoli;  Ni, Shuaishuai;  Chen, Feifei;  Mao, Fei;  Wei, Hanwen   |  收藏  |   Propofol inhibits hERG K+ channels and enhances the inhibition effects on its mutations in HEK293 cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 卷号: 791, 页码: 168-178 作者:  Han, Sheng-Na;  Jing, Ying;  Yang, Lin-Lin;  Zhang, Zhao;  Zhang, Li-Rong   |  收藏  |   Metabolism-based structure optimization: Discovery of a potent and orally available tyrosine kinase ALK inhibitor bearing the tetracyclic benzo[b]carbazolone core 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 22, 页码: 5399-5402 作者:  Han, Mei;  Wang, Chengyan;  Ji, Yinchun;  Song, Zilan;  Xing, Li   |  收藏  |   Cardiotoxicity screening: a review of rapid-throughput in vitro approaches 期刊论文  OAI收割 ARCHIVES OF TOXICOLOGY, 2016, 卷号: 90, 期号: 8, 页码: 1803-1816 作者:  Li, Xichun;  Zhang, Rui;  Zhao, Bin;  Lossin, Christoph;  Cao, Zhengyu 收藏  |   Lead compound optimization strategy (5) - reducing the hERG cardiac toxicity in drug development 期刊论文  OAI收割 Acta Pharmaceutica Sinica, 2016, 卷号: 51, 期号: 10, 页码: 1530-1539 作者:  Zhou Shengbin;  Wang Jiang;  Liu Hong   |  收藏  |   Design, synthesis and biological evaluation of 4-fluoropyrrolidine-2-carbonitrile and octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 86, 页码: 242-256 作者:  Ji, Xun;  Xia, Chunmei;  Wang, Jiang;  Su, Mingbo   |  收藏  |