中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [19]
金属研究所 [3]
昆明植物研究所 [1]
中国科学院大学 [1]
采集方式
OAI收割 [23]
iSwitch采集 [1]
内容类型
期刊论文 [24]
发表日期
2023 [1]
2022 [1]
2019 [2]
2018 [2]
2017 [1]
2016 [2]
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学科主题
Pharmacolo... [2]
Biochemist... [1]
Chemistry [1]
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共24条,第1-10条
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Development and validation of a LC-MS/MS method for quantitation of recombinant human growth hormone in rat plasma and application to a pharmacokinetic study
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 224, 页码: 9
作者:
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收藏
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浏览/下载:34/0
  |  
提交时间:2023/04/10
Recombinant human growth hormone (rhGH)
Somatotropin
Method validation
LC-MS
MS
Pharmacokinetics
Effects of Zuojin Pill (Rhizoma Coptidis and Fructus Evodiae preparation) on the pharmacokinetics and side effects of venlafaxine in humans
期刊论文
OAI收割
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2022, 卷号: 130, 期号: 4, 页码: 522-530
作者:
Yan, Dongmin
;
Wu, Ming
;
Hu, Wenjuan
;
Li, Yue
;
Jin, Jingyi
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收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/06/15
human
pharmacokinetics
side effect
venlafaxine
Zuojin Pill
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 卷号: 1122, 页码: 58-63
作者:
Hou, Xiangyu
;
Dai, Xiaojian
;
Yang, Yong
;
Zhang, Yifan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Imrecoxib
Imrecoxib active metabolites
Pharmacokinetics
LC-MS/MS
Human
Moderate impairment
Simultaneous determination of fosaprepitant and its metabolite aprepitant in human plasma by liquid chromatography-tandem mass spectrometry
期刊论文
OAI收割
Acta Pharmaceutica Sinica, 2018, 卷号: 53, 期号: 1, 页码: 121-126
作者:
SHEN Jia-le
;
ZAN Bin
;
CHEN Xiao-yan
;
ZHONG Da-fang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
LC-MS/MS
LC-MS/MS
fosaprepitant
aprepitant
stability
human pharmacokinetics
humanpharmacokineticsofginkgoterpenelactonesandimpactofcarboxylationinbloodontheirplateletactivatingfactorantagonisticactivity
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1935
作者:
Liu Xinwei
;
Yang Junling
;
Niu Wei
;
Jia Weiwei
;
Olaleye Olajide E
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
FACTOR PAF-ACETHER
ENDOTHELIAL-CELLS
BILOBA EXTRACTS
INHIBITION
METABOLISM
QUERCETIN
PLASMA
RUTIN
PON1
PARAOXONASES
Ginkgo biloba
human pharmacokinetics
renal excretion
terpene lactone
monocarboxylate
platelet-activating factor
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:
Yang, Na
;
Sun, Run-Bin
;
Chen, Xing-Long
;
Zhen, Le
;
Ge, Chun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2017/05/19
hyperglycemia
glucose-lowering effect
berberine
berberrubine
glucuronide
alpha-glycosidase
HFD-induced hyperglycemia model of C57BL/6 mice
human normal liver cell line L-O2
pharmacokinetics
Enfuvirtide-peg conjugate: a potent hiv fusion inhibitor with improved pharmacokinetic properties
期刊论文
iSwitch采集
European journal of medicinal chemistry, 2016, 卷号: 121, 页码: 232-237
作者:
Cheng, Shuihong
;
Wang, Yan
;
Zhang, Zhenxing
;
Lv, Xun
;
Gao, George F.
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/05/09
Conjugation
Enfuvirtide
Fusion inhibitor
Human immunodeficiency virus
Pharmacokinetics
Poly(ethylene glycol)
Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 4, 页码: 561
作者:
Liu Li
;
Miao Mingxing
;
Zhong Zeyu
;
Xu Ping
;
Chen Yang
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
VIVO ANTIBACTERIAL ACTIVITIES
DRUG-DRUG INTERACTIONS
HUMAN LIVER-MICROSOMES
IN-VIVO
CYTOCHROME-P450 ENZYMES
HEALTHY-VOLUNTEERS
COCKTAIL APPROACH
METABOLISM
QUINOLONE
CS-940
caderofloxacin
cocktail approach
chlorzoxazone
CYP2E1
pharmacokinetics
drug-drug interaction
Preclinical pharmacokinetics of TPN729MA, a novel PDE5 inhibitor, and prediction of its human pharmacokinetics using a PBPK model
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 12, 页码: 1528-1536
作者:
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收藏
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浏览/下载:42/0
  |  
提交时间:2019/01/08
TPN729MA
PDE5 inhibitor
erectile dysfunction
pharmacokinetics
human PK prediction
physiologically based pharmacokinetic model